[PDF][PDF] The Assessment of Methods for Preimplantation Genetic Testing for Aneuploidies (PGT-A) Using a Universal Parameter: Implications for Costs and Mosaicism …

A Belyaev, M Tofilo, S Popov, I Mazunin, D Fomin - 2024 - scholar.archive.org
Preimplantation genetic testing for aneuploidies (PGT-A) is used to increase live birth rates
following in vitro fertilization. The assessment of different PGT-A methods to date has relied …

[HTML][HTML] The Assessment of Methods for Preimplantation Genetic Testing for Aneuploidies Using a Universal Parameter: Implications for Costs and Mosaicism …

A Belyaev, M Tofilo, S Popov, I Mazunin… - … of Biotechnology and …, 2024 - fortunepublish.com
Preimplantation genetic testing for aneuploidies (PGT-A) is used to increase live birth rates
following in vitro fertilization. The assessment of different PGT-A methods to date has relied …

P-744 Reporting chromosomal mosaicism reduces the overall accuracy of preimplantation genetic testing for aneuploidies: results from the extended in vitro culture of …

M Popovic, F Azpiroz, A Pujol, B Lledó… - Human …, 2023 - academic.oup.com
Study question What is the accuracy of reporting chromosomal mosaicism in the context of
next generation sequencing (NGS)-based preimplantation genetic testing for aneuploidies …

REPORTING CHROMOSOMAL MOSAICISM REDUCES THE DIAGNOSTIC ACCURACY OF PREIMPLANTATION GENETIC TESTING: RESULTS FROM THE …

M Popovic, FM Azpiroz, MT Massana, AQ Vehí… - Fertility and …, 2023 - fertstert.org
OBJECTIVE Preimplantation genetic testing for aneuploidies (PGT-A) aims to improve
clinical outcomes. However, diagnostic accuracy remains a concern, particularly when …

2. Clinical comparison of two PGT-A platforms utilizing different thresholds to determine ploidy status

D Monahan, G Harton, D Griffin, M Angle… - Reproductive BioMedicine …, 2019 - Elsevier
Introduction Unlike previous technologies that lack the diagnostic performance to reliably
detect mosaicism for preimplantation genetic testing for aneuploidy (PGT-A), next generation …

VARIABILITY IN THE INCIDENCE OF UNUSABLE RESULTS BY PREIMPLANTATION GENETIC TESTING: MULTI-LAB COMPARATIVE ANALYSIS

M Jimenez, A Cooper, M Viotti - Fertility and Sterility, 2024 - fertstert.org
Background The enhancements to reproductive medicine conferred by Preimplantation
Genetic Testing for Aneuploidy (PGT-A) hinge on the test delivering clinically relevant …

Preimplantation genetic testing for aneuploidy: current perspectives

A L'Heveder, BP Jones, R Naja… - Seminars in …, 2021 - thieme-connect.com
Despite improvements in assisted reproduction techniques (ARTs), live birth rates remain
suboptimal, particularly in women with advanced maternal age (AMA). The leading cause of …

Aneuploidy screening using next generation sequencing

C Cinnioglu, R Kayali, T Darvin, A Akinwole… - Prenatal Diagnosis, 2019 - Springer
Chromosomal aneuploidy is recognized to be a significant contributing factor in implantation
failure and spontaneous miscarriage Hellani et al.(Reprod Biomed Online 17: 841–847 …

EXTENDED IN VITRO CULTURE OF HUMAN EMBRYOS DEMONSTRATES THE POOR PREDICTIVE VALUE OF DIAGNOSING CHROMOSOMAL MOSAICISM …

M Popovic, F Azpiroz, AP Masana, AR Aranda… - Fertility and …, 2022 - fertstert.org
Objective Preimplantation genetic testing for aneuploidies (PGT-A) has been introduced into
clinical practice to improve outcomes. However, diagnostic accuracy remains controversial …

Discrepancy in PGT-A results among different genetic reference laboratories: how accurate are the results and are we discarding euploid embryos?

F Sharara, M Goodwin, GA Abdo - Fertility and Sterility, 2018 - fertstert.org
Objective The use of pre-implantation genetic testing for aneuploidy (PGT-A) has been
increasing steadily for the past few years. The policy of most programs is to discard …