The Wernicke conundrum and the anatomy of language comprehension in primary progressive aphasia

MM Mesulam, CK Thompson, S Weintraub… - Brain, 2015 - academic.oup.com
Wernicke's aphasia is characterized by severe word and sentence comprehension
impairments. The location of the underlying lesion site, known as Wernicke's area, remains …

Words and objects at the tip of the left temporal lobe in primary progressive aphasia

MM Mesulam, C Wieneke, R Hurley, A Rademaker… - Brain, 2013 - academic.oup.com
Eleven of 69 prospectively enrolled primary progressive aphasics were selected for this
study because of peak atrophy sites located predominantly or exclusively within the anterior …

Wernicke's aphasia reflects a combination of acoustic-phonological and semantic control deficits: a case-series comparison of Wernicke's aphasia, semantic dementia …

H Robson, K Sage, MAL Ralph - Neuropsychologia, 2012 - Elsevier
Wernicke's aphasia (WA) is the classical neurological model of comprehension impairment
and, as a result, the posterior temporal lobe is assumed to be critical to semantic cognition …

Word comprehension in temporal cortex and Wernicke area: A PPA perspective

MM Mesulam, BM Rader, J Sridhar, MJ Nelson… - Neurology, 2019 - AAN Enterprises
Objective To explore atrophy–deficit correlations of word comprehension and repetition in
temporoparietal cortices encompassing the Wernicke area, based on patients with primary …

The anterior temporal lobes support residual comprehension in Wernicke's aphasia

H Robson, R Zahn, JL Keidel, RJ Binney, K Sage… - Brain, 2014 - academic.oup.com
Wernicke's aphasia occurs after a stroke to classical language comprehension regions in
the left temporoparietal cortex. Consequently, auditory–verbal comprehension is …

Neural mechanisms of object naming and word comprehension in primary progressive aphasia

RS Hurley, KA Paller, EJ Rogalski… - Journal of …, 2012 - Soc Neuroscience
Primary progressive aphasia (PPA) is a neurodegenerative syndrome that causes a gradual
atrophy of the left hemisphere language network, leading to impairments of object naming …

Varieties of semantic 'access' deficit in Wernicke's aphasia and semantic aphasia

HE Thompson, H Robson, MA Lambon Ralph… - Brain, 2015 - academic.oup.com
Comprehension deficits are common in stroke aphasia, including in cases with (i) semantic
aphasia, characterized by poor executive control of semantic processing across verbal and …

Anatomy of aphasia revisited

J Fridriksson, DB den Ouden, AE Hillis, G Hickok… - Brain, 2018 - academic.oup.com
In most cases, aphasia is caused by strokes involving the left hemisphere, with more
extensive damage typically being associated with more severe aphasia. The classical model …

Recovery from Wernicke's aphasia: a positron emission tomographic study

C Weiller, C Isensee, M Rijntjes… - Annals of Neurology …, 1995 - Wiley Online Library
Abstract Changes in the organization of the brain after recovery from aphasia were
investigated by measuring increases in regional cerebral blood flow (rCBF) during repetition …

Naming and comprehension in primary progressive aphasia: The influence of grammatical word class

AE Hillis, J Heidler‐Gary, M Newhart, S Chang… - Aphasiology, 2006 - Taylor & Francis
Background: Various clinical types of primary progressive aphasia have been associated
with distinct areas of atrophy and pathological changes. Therefore, differences in the …