[HTML][HTML] Reducing neuroinflammation via therapeutic compounds and lifestyle to prevent or delay progression of Parkinson's disease

E Kip, LC Parr-Brownlie - Ageing Research Reviews, 2022 - Elsevier
Parkinson's disease (PD) is the second most common age-associated neurodegenerative
disorder and is characterised by progressive loss of dopamine neurons in the substantia …

[HTML][HTML] Parkinson's disease: Can targeting inflammation be an effective neuroprotective strategy?

V Gundersen - Frontiers in neuroscience, 2021 - frontiersin.org
The reason why dopamine neurons die in Parkinson's disease remains largely unknown.
Emerging evidence points to a role for brain inflammation in neurodegeneration. Essential …

Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

MG Tansey, MS Goldberg - Neurobiology of disease, 2010 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease, after
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies …

Peripheral immunity, immunoaging and neuroinflammation in Parkinson's disease

N Kustrimovic, F Marino… - Current Medicinal …, 2019 - ingentaconnect.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder among
elderly population, characterized by the progressive degeneration of dopaminergic neurons …

Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson's disease

RL Mosley, EJ Benner, I Kadiu, M Thomas… - Clinical neuroscience …, 2006 - Elsevier
Neuroinflammatory processes play a significant role in the pathogenesis of Parkinson's
disease (PD). Epidemiologic, animal, human, and therapeutic studies all support the …

Inflammatory mechanisms in Parkinson's disease: from pathogenesis to targeted therapies

SYH Lee, NJ Yates, SJ Tye - The Neuroscientist, 2022 - journals.sagepub.com
Inflammation is a critical factor contributing to the progressive neurodegenerative process
observed in Parkinson's disease (PD). Microglia, the immune cells of the central nervous …

Oxidative stress and neuroinflammation in the story of Parkinson's disease: could targeting these pathways write a good ending?

K Hassanzadeh, A Rahimmi - Journal of cellular physiology, 2019 - Wiley Online Library
Although, current medications for Parkinson's disease can control and relief symptoms of the
disease efficiently, they are unable to either prevent progression of the disease or maintain …

Neurodegeneration and inflammation in Parkinson's disease

S Phani, JD Loike, S Przedborski - Parkinsonism & related disorders, 2012 - Elsevier
Parkinson's disease (PD) is characterized by the progressive degeneration of dopamine
(DA) neurons of the substantia nigra pars compacta (SNpc) accompanied by a buildup of …

[HTML][HTML] Inflammation and immune dysfunction in Parkinson disease

MG Tansey, RL Wallings, MC Houser… - Nature Reviews …, 2022 - nature.com
Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral
organs as well as the central nervous system and involves a fundamental role of …

Parkinson′ s disease and systemic inflammation

CC Ferrari, R Tarelli - Parkinson's disease, 2011 - Wiley Online Library
Peripheral inflammation triggers exacerbation in the central brain′ s ongoing damage in
several neurodegenerative diseases. Systemic inflammatory stimulus induce a general …