Introduction Polypharmacy, which uses multiple medications to treat chronic illnesses, is
common among elderly patients. However, it can lead to drug interactions, especially with …

Opinion statement The careful review of drug-drug interactions is vital to the safe prescribing
of medications for chronic medical conditions. The elderly population suffers from multiple …

Background It has been hypothesized that polypharmacy may increase the frequency of
multidrug interactions (MDIs) where one drug interacts with two or more other drugs …

BACKGROUND: Elderly patients are vulnerable to drug interactions because of age-related
physiologic changes, an increased risk for disease associated with aging, and the …

Older patients are at high risk for food-drug Interactions. These patients are commonly on
multiple medications for chronic medical conditions. Age-related physiologic changes …

Gastrointestinal (GI) manifestations in older adults can be caused or alleviated by drug
therapy. GI medications, such as proton pump inhibitors and histamine-2 receptor …

Drug interactions occur when the concomitant administration of another drug or substance
affects a drug's effect. The results of these interactions range on a scale of clinical …

Older patients are prone to multimorbidity or related polypharmacy, which may cause
various adverse drug reactions (ADRs) and a high incidence of drug‐related health …

BACKGROUND:: Older adults may have decreased homeostatic reserve, have multiple
chronic diseases, and take multiple medications. Therefore, they are at risk for adverse …

The simultaneous use of multiple drugs—termed 'polypharmacy'—is often required to
manage multiple physiological and biological changes and the interplay between chronic …