There has been a considerable improvement in the media available for the culture of
preimplantation mouse embryos during the 40 years since mouse embryos were first …

We have recently reported the use of sequential simplex optimization methods to design a
medium (SOM) that overcomes the block to development beyond two cells which occurs in …

Methods for the culture of preimplantation human embryos evolved primarily from those
used for mouse embryos. The initial method was usually culture in a single medium in …

Considerable advances in media development for the culture of preimplantation mammalian
embryos have been made since mouse embryos were first cultured and successfully …

There are several treatises on the composition of embryo culture media and the role of
specific medium components in supporting mammalian embryo development in vitro (1–3). It …

In the fast pace and competitiveness of modern science, there is less and less time to teach
students the background on how the currently used scientific methods and ideas came …

Since the inception of modern embryo culture media over 50 years ago there have been
significant developments in culture systems for the mammalian preimplantation embryo …

The culture conditions for the development in vitro of (C57BL/6 X CBA) F2 hybrid two-cell
embryos to the blastocyst stage have been optimized. Commercially available pre-sterile …

BACKGROUND: A comparison has been made of the development of mouse zygotes in
either one-step or two-step culture systems. METHODS: Embryo culture, blastocyst cell …

As mentioned in the Preface to this book, most of what we presently know about the
regulation of preimplantation embryo development is derived from studies with mouse …