Viruses, friends, and foes: The case of Torque Teno Virus and the net state of immunosuppression

N Redondo, D Navarro, JM Aguado… - Transplant Infectious …, 2022 - Wiley Online Library
New reliable biomarkers are needed to improve individual risk assessment for post‐
transplant infection, acute graft rejection and other immune‐related complications after solid …

Torque teno virus as a potential biomarker for complications and survival after allogeneic hematopoietic stem cell transplantation

A Pradier, S Masouridi-Levrat, C Bosshard… - Frontiers in …, 2020 - frontiersin.org
Impaired immune reconstitution after allogeneic hematopoietic stem cell transplantation
(HSCT) contributes to increased risk of cancer relapse and infection resulting in significant …

Dynamics of Torque Teno virus plasma DNAemia in allogeneic stem cell transplant recipients

E Albert, C Solano, T Pascual, I Torres, L Macera… - Journal of Clinical …, 2017 - Elsevier
Abstract Background Torque Teno virus (TTV) plasma DNA load directly correlate with the
level of immunosuppresion in different clinical settings. It is uncertain whether this may be …

Dynamics of Torque Teno virus viremia could predict risk of complications after allogeneic hematopoietic stem cell transplantation

R Gilles, M Herling, U Holtick, E Heger… - Medical microbiology …, 2017 - Springer
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an established treatment
option for several hematological diseases. However, the first year post-transplantation is …

[HTML][HTML] Torque teno virus loads after kidney transplantation predict allograft rejection but not viral infection

AL van Rijn, HF Wunderink, IA Sidorov… - Journal of Clinical …, 2021 - Elsevier
The main challenge of immunosuppressive therapy after solid organ transplantation is to
create a new immunological balance that prevents organ rejection and does not promote …

[HTML][HTML] The value of torque teno virus (TTV) as a marker for the degree of immunosuppression in adult patients after hematopoietic stem cell transplantation (HSCT)

J Schmitz, G Kobbe, M Kondakci, E Schuler… - Biology of Blood and …, 2020 - Elsevier
Torque teno virus (TTV) is a nonenveloped, single-stranded, circular DNA virus of the family
of Anelloviridae. The first contact with TTV usually occurs in early childhood, followed by …

[HTML][HTML] Torque teno virus for risk stratification of graft rejection and infection in kidney transplant recipients—a prospective observational trial

K Doberer, M Schiemann, R Strassl… - American Journal of …, 2020 - Elsevier
The nonpathogenic and ubiquitous torque teno virus (TTV) is associated with
immunosuppression in solid organ transplant recipients. Studies in kidney transplant …

Torque teno virus as a novel biomarker targeting the efficacy of immunosuppression after lung transplantation

P Jaksch, M Kundi, I Görzer, G Muraközy… - The Journal of …, 2018 - academic.oup.com
Torque teno viruses (TTV) are small DNA-viruses, of the genus Alphatorquevirus, whose
replication is linked to immune status. TTV load may be an indicator for efficacy of IS in lung …

Quantification of torque teno virus viremia as a prospective biomarker for infectious disease in kidney allograft recipients

R Strassl, M Schiemann, K Doberer… - The Journal of …, 2018 - academic.oup.com
Background Drug-induced immunosuppression following kidney transplantation is crucial to
prevent allograft rejection, but increases risk for infectious disease. Tailoring of drug dosing …

Torque teno virus viral load as a marker of immune function in allogeneic haematopoietic stem cell transplantation recipients

W Mouton, A Conrad, A Bal, M Boccard, C Malcus… - Viruses, 2020 - mdpi.com
Torque teno virus (TTV) has been proposed as a surrogate biomarker of T-cell function in
allogeneic–haematopoietic–stem-cell transplantation (allo-HSCT). Conflicting data exists …