[HTML][HTML] Transcriptomics and flow cytometry reveals the cytotoxicity of aflatoxin B1 and aflatoxin M1 in bovine mammary epithelial cells

K Wu, S Jia, J Zhang, C Zhang, S Wang… - Ecotoxicology and …, 2021 - Elsevier
Aflatoxin is a known mycotoxin that pollutes various grains widely in the environment.
Aflatoxin B 1 (AFB 1) and Aflatoxin M 1 (AFM 1) have been shown to induce cytotoxicity in …

Exposure to aflatoxin B1 attenuates cell viability and induces endoplasmic reticulum-mediated cell death in a bovine mammary epithelial cell line (MAC-T)

W Park, MY Park, G Song, W Lim - Toxicology in Vitro, 2019 - Elsevier
Mammary gland epithelial cells play a key role in milk production in dairy cattle, which are
prone to feed contamination from microorganisms, especially pathogenic fungi and their …

Multi-omics reveal additive cytotoxicity effects of aflatoxin B1 and aflatoxin M1 toward intestinal NCM460 cells

YN Gao, X Yang, JQ Wang, HM Liu, N Zheng - Toxins, 2022 - mdpi.com
Aflatoxin B1 (AFB1) is a common crop contaminant, while aflatoxin M1 (AFM1) is implicated
in milk safety. Humans are likely to be simultaneously exposed to AFB1 and AFM1; however …

Insights into Aflatoxin B1 Toxicity in Cattle: An in vitro whole-transcriptomic approach

M Pauletto, R Tolosi, M Giantin, G Guerra… - Toxins, 2020 - mdpi.com
Aflatoxins, and particularly aflatoxin B1 (AFB1), are toxic mycotoxins to humans and farm
animal species, resulting in acute and chronic toxicities. At present, AFB1 is still considered …

Whole-transcriptome analysis of non-coding RNA alteration in porcine alveolar macrophage exposed to aflatoxin B1

H Chao, H Ma, J Sun, S Yuan, P Dong, A Zhao, L Li… - Toxins, 2022 - mdpi.com
Aflatoxin B1 (AFB1) is a type of mycotoxin produced by the fungi Aspergillus flavus and
Aspergillus parasiticus and is commonly found in cereals, oils and foodstuffs. In order to …

Research progress in toxicological effects and mechanism of aflatoxin B1 toxin

C Li, X Liu, J Wu, X Ji, Q Xu - PeerJ, 2022 - peerj.com
Fungal contamination of animal feed can severely affect the health of farm animals, and
result in considerable economic losses. Certain filamentous fungi or molds produce toxic …

Effects of aflatoxin B1 on human breast cancer (MCF-7) cells: cytotoxicity, oxidative damage, metabolic, and immune-modulatory transcriptomic changes

A Aljazzar, WR El-Ghareeb, WS Darwish… - … Science and Pollution …, 2023 - Springer
Abstract Aflatoxin B1 (AFB1) is a potent mycotoxin that is commonly produced by molds such
as Aspergillus (A.) flavus and A. parasiticus. AFB1 is associated with several health adverse …

[HTML][HTML] Transcriptome analysis revealed that aflatoxin M1 could cause cell cycle arrest in differentiated Caco-2 cells

XY Bao, SL Li, YN Gao, JQ Wang, N Zheng - Toxicology in Vitro, 2019 - Elsevier
Being a hydroxylated metabolite of aflatoxin B1 (AFB1) and the most threatening aspect of
AFB1 contamination, aflatoxin M1 (AFM1) can lead to hepatotoxicity and hepato …

[HTML][HTML] Aflatoxin B1 affects apoptosis and expression of death receptor and endoplasmic reticulum molecules in chicken spleen

P Zhu, Z Zuo, Z Zheng, F Wang, X Peng, J Fang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Aflatoxin B 1 (AFB 1) is a natural product of the Aspergillus genus of molds, which
grow on several foodstuffs stored in hot moist conditions, and is among the most potent …

The toxic effect of aflatoxin B1 on early porcine embryonic development

KT Shin, J Guo, YJ Niu, XS Cui - Theriogenology, 2018 - Elsevier
Abstract Aflatoxin B1 (AFB1) is a type of mycotoxin produced by the fungi Aspergillus flavus
and Aspergillus parasiticus. AFB1 is considered as the most toxic mycotoxin owing to its …