Introduction Osteoarthritis (OA) is a prevalent joint disorder characterized by multifaceted
pathogenesis, with macrophage dysregulation playing a critical role in perpetuating …

Background Osthole (OST), a characteristic coumarin compound in Angelicae pubescentis
radix (APR), has shown potent efficacy in the treatment of rheumatoid arthritis (RA), but its …

Osteoarthritis (OA) is a chronic degenerative disease that commonly affects the elderly.
Current drug therapies for treating OA may cause adverse side effects, and so there remains …

Osteoarthritis (OA) is a common degenerative disease worldwide and new therapeutics that
target inflammation and the crosstalk between immunocytes and chondrocytes are being …

Osteoarthritis (OA) is a long‐term and inflammatory disorder featured by cartilage erosion.
Here, we describe nomilin (NOM), a triterpenoid with inflammation modulatory properties in …

Rheumatoid arthritis (RA) is a chronic autoimmune, multifactorial, inflammatory disorder
characterized by hyperplasia and infiltration of inflammatory cells at the synovial lining …

Post-trauma osteoarthritis (PTOA) is the most common articular disease characterized by
degeneration and destruction of articular cartilage (Bultink and Lems, Curr. Rheumatol Rep …

Osteoarthritis (OA) is a widespread chronic degenerative joint disease characterized by the
degeneration of articular cartilage or inflamed joints. Our findings indicated that treatment …

Ethnopharmacological relevance Glycine tabacina (Labill.) Benth has been used as a
traditional Chinese herbal medicine for the treatment of rheumatoid arthritis (RA) and joint …

Osteoarthritis (OA) is the most common joint disorder, and disease-modifying OA drugs
(DMOADs) represent a major need in OA management. Krüppel-like factor 4 (KLF4) is a …