RNA interference: biology, mechanism, and applications

N Agrawal, PVN Dasaradhi, A Mohmmed… - Microbiology and …, 2003 - Am Soc Microbiol
Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of
silencing gene expression in a range of organisms. The silencing of a gene is a …

RNA interference: historical overview and significance

MK Montgomery - RNA Interference, Editing, and Modification: Methods …, 2004 - Springer
In the early 1990s, attempts to manipulate gene expression by researchers working in three
different fields resulted in unanticipated gene silencing. Rather than ignoring such results …

RNA interference: past, present and future

TN Campbell, FYM Choy - Current issues in molecular biology, 2005 - mdpi.com
RNA interference (RNAi) is the sequence-specific gene silencing induced by double-
stranded RNA. RNAi is mediated by 21-23 nucleotide small interfering RNAs (siRNAs) …

RNA silencing and the mobile silencing signal

S Mlotshwa, O Voinnet, MF Mette, M Matzke… - The Plant …, 2002 - academic.oup.com
RNA silencing is a sequence-specific RNA degradation mechanism that occurs in a broad
range of eukaryotic organisms including fungi (quelling), animals (RNA interference [RNAi]) …

[HTML][HTML] Dicing and slicing: the core machinery of the RNA interference pathway

SM Hammond - FEBS letters, 2005 - Elsevier
RNA interference (RNAi) is broadly defined as a gene silencing pathway that is triggered by
double-stranded RNA (dsRNA). Many variations have been described on this theme. The …

RNA interference in crop plants

M Kusaba - Current opinion in Biotechnology, 2004 - Elsevier
RNA interference (RNAi) is a post-transcriptional gene-silencing phenomenon induced by
double-stranded RNA. It has been widely used as a knockdown technology to analyze gene …

The genetics of RNA silencing

M Tijsterman, RF Ketting… - Annual Review of …, 2002 - annualreviews.org
▪ Abstract Although initially recognized as a handy tool to reduce gene expression, RNA
silencing, triggered by double-stranded RNA molecules, is now recognized as a mechanism …

[HTML][HTML] Two classes of short interfering RNA in RNA silencing

A Hamilton, O Voinnet, L Chappell… - The EMBO journal, 2002 - embopress.org
RNA silencing is a eukaryotic genome defence system that involves processing of double‐
stranded RNA (dsRNA) into 21–26 nt, short interfering RNA (siRNA). The siRNA mediates …

RNA interference: the molecular immune system

O Bagasra, KR Prilliman - Journal of molecular histology, 2004 - Springer
Introduction of double-stranded RNA (dsRNA) into cells expressing a homologous gene
triggers RNA interference (RNAi), or RNA-based gene silencing (RBGS). The dsRNA …

Redundancy of the Two Dicer Genes in Transgene-Induced Posttranscriptional Gene Silencing in Neurospora crassa

C Catalanotto, M Pallotta, P ReFalo… - … and cellular biology, 2004 - Taylor & Francis
RNA interference (RNAi) in animals, cosuppression in plants, and quelling in fungi are
homology-dependent gene silencing mechanisms in which the introduction of either double …