Membrane lipid domains and dynamics as detected by Laurdan fluorescence

T Parasassi, E Gratton - Journal of fluorescence, 1995 - Springer
Dimethylamino-6-lauroylnaphthalene (Laurdan) is a membrane probe of recent
characterization, which shows high sensitivity to the polarity of its environment. Steady-state …

[PDF][PDF] Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence

T Parasassi, G De Stasio, A d'Ubaldo, E Gratton - Biophysical journal, 1990 - cell.com
The organization of lipids surrounding membrane proteins can influence their properties. We
have used 6-dodecanoyl-2-dimethylaminonaphthalene (Laurdan) to study phase …

[PDF][PDF] Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence

T Parasassi, G De Stasio, G Ravagnan, RM Rusch… - Biophysical journal, 1991 - cell.com
The sensitivity of Laurdan (6-dodecanoyl-2-dimethylaminonaphthalene) excitation and
emission spectra to the physical state of the membrane arises from dipolar relaxation …

[PDF][PDF] Influence of cholesterol on phospholipid bilayers phase domains as detected by Laurdan fluorescence

T Parasassi, M Di Stefano, M Loiero, G Ravagnan… - Biophysical …, 1994 - cell.com
Coexisting gel and liquid-crystalline phospholipid phase domains can be observed in
synthetic phospholipid vesicles during the transition from one phase to the other and, in …

[HTML][HTML] Use of laurdan fluorescence intensity and polarization to distinguish between changes in membrane fluidity and phospholipid order

FM Harris, KB Best, JD Bell - Biochimica et Biophysica Acta (BBA) …, 2002 - Elsevier
Laurdan is a fluorescent probe that detects changes in membrane phase properties through
its sensitivity to the polarity of its environment in the bilayer. Variations in membrane water …

Modulation and dynamics of phase properties in phospholipid mixtures detected by Laurdan fluorescence

T Parasassi, G Ravagnan, RM Rusch… - Photochemistry and …, 1993 - Wiley Online Library
Steady‐state and dynamic fluorescence properties of 6‐lauroyl‐2‐
dimethylaminonaphthalene (Laurdan) have been used to ascertain the coexistence of …

[HTML][HTML] Prodan as a membrane surface fluorescence probe: partitioning between water and phospholipid phases

EK Krasnowska, E Gratton, T Parasassi - Biophysical journal, 1998 - cell.com
Fluorescence spectral features of 6-propionyl-2-dimethylaminonaphthalene (Prodan) in
phospholipid vesicles of different phase states are investigated. Like the spectra of 6-lauroyl …

LAURDAN since Weber: The quest for visualizing membrane heterogeneity

G Gunther, L Malacrida, DM Jameson… - Accounts of chemical …, 2021 - ACS Publications
Conspectus Any chemist studying the interaction of molecules with lipid assemblies will
eventually be confronted by the topic of membrane bilayer heterogeneity and may ultimately …

[PDF][PDF] Abrupt modifications of phospholipid bilayer properties at critical cholesterol concentrations

T Parasassi, AM Giusti, M Raimondi, E Gratton - Biophysical journal, 1995 - cell.com
The fluorescence generalized polarization (GP) of 2-dimethylamino-6-lauroylnaphthalene
(Laurdan) reveals different effects of cholesterol on the phase behavior of phospholipid …

[PDF][PDF] Cholesterol modifies water concentration and dynamics in phospholipid bilayers: a fluorescence study using Laurdan probe

T Parasassi, M Di Stefano, M Loiero, G Ravagnan… - Biophysical journal, 1994 - cell.com
The effect of cholesterol on the gel, the liquid-crystalline, and mixed phospholipid phases
has been studied using the fluorescence properties of 2-dimethylamino-6 …