Induction chemotherapy in locally advanced head and neck cancers, is there a best choice?

H Mahdavi - Critical Reviews in Oncology/Hematology, 2023 - Elsevier
Locally advanced stages of squamous cancers of the head and neck (LAHNCs) acquire
high propensity for local and systemic relapse. Addition of systemic therapy as an induction …

Induction therapy in the modern era of combined-modality therapy for locally advanced head and neck cancer

M Posner, JB Vermorken - Seminars in oncology, 2008 - Elsevier
As therapy for locoregionally advanced head and neck cancer (HNC) has evolved, treatment
has become increasingly aggressive and cure rates have risen. However, survival still …

Induction chemotherapy for locoregionally advanced head and neck cancer: past, present, future?

GJ Hanna, RI Haddad, JH Lorch - The Oncologist, 2013 - academic.oup.com
The treatment of patients with locoregionally advanced squamous cell cancer of the head
and neck is still evolving. Induction chemotherapy (IC) is widely used in this patient …

New options in the treatment of locally advanced head and neck cancer: role for induction chemotherapy

JJ Cruz, A Ocaña, M Navarro, E Del Barco… - Cancer treatment …, 2008 - Elsevier
Advanced locoregional disease is the most frequent clinical situation in Head and Neck
cancer. The standard of care for most clinicians is a multidisciplinary treatment with …

The current role of systemic chemotherapy in the primary treatment of head and neck cancer

CJ Busch, S Tribius, P Schafhausen, R Knecht - Cancer treatment reviews, 2015 - Elsevier
The treatment of patients with locoregionally advanced squamous cell carcinoma of the
head and neck (HNSCC) is still evolving into the perfect combination of the different …

[HTML][HTML] Induction chemotherapy in locally advanced squamous cell carcinoma of the head and neck: role, controversy, and future directions

RI Haddad, M Posner, R Hitt, EEW Cohen, J Schulten… - Annals of …, 2018 - Elsevier
Background The value of induction chemotherapy (ICT) remains under investigation despite
decades of research. New advancements in the field, specifically regarding the induction …

[HTML][HTML] The slippery role of induction chemotherapy in head and neck cancer: myth and reality

D Ferrari, MG Ghi, C Franzese, C Codecà… - Frontiers in …, 2020 - frontiersin.org
Chemoradiotherapy as an alternative to surgery can be offered to patients affected by loco-
regionally advanced head and neck cancer (HNC). Induction chemotherapy is a valid …

Induction chemotherapy for head and neck cancer: recent data

EE Vokes - The oncologist, 2010 - academic.oup.com
The addition of chemotherapy to radiotherapy in the treatment of locally advanced
squamous cell carcinoma of the head and neck (SCCHN) patients improves survival. Meta …

[HTML][HTML] Revisiting induction chemotherapy for head and neck cancer

A Argiris, P Jayaram, D Pichardo - Oncology (Williston Park), 2005 - cgtlive.com
Squamous cell carcinomas of the head and neck are highly responsiveto induction
chemotherapy. However, randomized trials have failedto demonstrate a survival advantage …

Phase II/III trial of induction chemotherapy (ICT) with cisplatin/5-fluorouracil (PF) vs. docetaxel (T) plus PF (TPF) followed by chemoradiotherapy (CRT) vs. CRT for …

R Hitt, J Grau, A Lopez-Pousa, A Berrocal… - Journal of Clinical …, 2005 - ascopubs.org
5578 Background: Induction chemotherapy plus CRT vs. CRT as front line treatment have
not been compare in LAHNC in randomised study. Recently, Zorat et al reported benefit in …