Design, Synthesis and Cytotoxicity of New Coumarin‐1, 2, 3‐triazole Derivatives: Evaluation of Anticancer Activity and Molecular Docking Studies
V Premsagar Miriyala, P Raj Thommandru… - Chemistry & …, 2023 - Wiley Online Library
A library of new coumarin‐1, 2, 3‐triazole hybrids 7a–l were synthesized from 4‐
(diethylamino)‐2‐hydroxybenzaldehyde precursor through a series of reactions including …
(diethylamino)‐2‐hydroxybenzaldehyde precursor through a series of reactions including …
Synthesis and biological evaluation of novel triazoles linked 7-hydroxycoumarin as potent cytotoxic agents
S Farooq, A Hussain, MA Qurishi… - Anti-Cancer Agents in …, 2018 - ingentaconnect.com
Background: BacCancer is regarded as second leading cause of death worldwide.
Therefore, there is a high demand for the discovery, development and improvement of novel …
Therefore, there is a high demand for the discovery, development and improvement of novel …
Synthesis and biological evaluation of novel isoxazoles and triazoles linked 6-hydroxycoumarin as potent cytotoxic agents
A new series of diverse isoxazoles and triazoles linked 6-hydroxycoumarin (1) were
synthesized using click chemistry approach. All the derivatives were subjected to 3-(4, 5 …
synthesized using click chemistry approach. All the derivatives were subjected to 3-(4, 5 …
Synthesis of Novel 1, 2, 4‐Triazolyl Coumarin Derivatives as Potential Anticancer Agents
LH Al-Wahaibi, HM Abu-Melha… - Journal of …, 2018 - Wiley Online Library
A series of novel coumarin derivatives carrying 1, 2, 4‐triazole or 1, 2, 4‐triazolo [3, 4‐b][1, 3,
4] thiadiazole moieties were prepared and evaluated in vitro as anticancer in the human …
4] thiadiazole moieties were prepared and evaluated in vitro as anticancer in the human …
Synthesis of 4‐Hydroxycoumarin‐Based Triazoles/Oxadiazoles as Novel Anticancer Agents
SM Hashemi, Z Hosseini‐khah… - Chemistry & …, 2022 - Wiley Online Library
A series of novel 3‐substituted‐4‐hydroxycoumarins 7 and 8 containing (5‐aryl‐1, 3, 4‐
oxadiazol‐2‐yl) thio or (4‐amino‐5‐aryl‐4H‐1, 2, 4‐triazol‐3‐yl) thio moieties have been …
oxadiazol‐2‐yl) thio or (4‐amino‐5‐aryl‐4H‐1, 2, 4‐triazol‐3‐yl) thio moieties have been …
Synthesis and anticancer activities of some new coumarin derivatives including the triazole ring and their in silico molecular docking studies
The synthesis, docking study, and investigation of the anticancer activities of some coumarin
derivatives containing the triazole ring are reported in this study. The newly synthesized …
derivatives containing the triazole ring are reported in this study. The newly synthesized …
Design, synthesis and cytotoxicity of novel coumarin-1, 2, 3-triazole-1, 2, 4-oxadiazole hybrids as potent anti-breast cancer agents
M Mohammadi-Khanaposhtani… - Letters in Drug …, 2019 - ingentaconnect.com
Background: This work reports design, synthesis, and in vitro cytotoxicity of novel coumarin-
1, 2, 3-triazole-1, 2, 4-oxadiazole hybrids against three breast cancer cell lines MCF-7, MDA …
1, 2, 3-triazole-1, 2, 4-oxadiazole hybrids against three breast cancer cell lines MCF-7, MDA …
Synthesis of pyrazolone derivatives of coumarin as anticancer agents
JV Patil, SS Soman, S Umar, P Girase… - …, 2024 - Wiley Online Library
Pursuing on our efforts towards searching for efficient anticancer agents herein we have
designed and synthesized pyrazolone derivatives of 7‐amino 4‐methyl coumarin and 6 …
designed and synthesized pyrazolone derivatives of 7‐amino 4‐methyl coumarin and 6 …
Synthesis, antitumor activity evaluation, and DNA‐binding study of coumarin‐based agents
A novel series of coumarin‐thiadiazole heterocycle derivatives was synthesized by the
nucleophilic substitution reaction. The synthesized compounds were structurally verified by …
nucleophilic substitution reaction. The synthesized compounds were structurally verified by …
Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1, 2, 3-triazole–coumarin hybrids
Abstract The 4-substituted 1, 2, 3-triazole core in designed coumarin hybrids (4–35) with
diverse physicochemical properties was introduced by eco-friendly copper (I)-catalyzed …
diverse physicochemical properties was introduced by eco-friendly copper (I)-catalyzed …