The causal role of an elevated serum cholesterol level in the genesis of atherosclerosis and
its clinical sequelae, particularly ischemic heart disease, is now well established. The …

The primary aim of this study was to estimate the relation between cholesterol reduction and
total mortality and coronary heart disease (CHD) incidence. Secondarily, the clinical issues …

In the more than 50 years since the founding of the National Heart, Lung, and Blood Institute
and the American Heart Association, medical science has moved from an era in which …

A review of the experimental clinical trials and observational cohort evidence relating serum
cholesterol level and its reduction to risks of coronary heart disease (CHD) discloses strong …

Atherosclerotic vascular disease is the major cause of death and disability in adult men and
women living in the United States, where 13–14 million adults have a history of coronary …

CURRENT recommendations for lowering the cholesterol level to prevent coronary heart
disease have focused largely on primary prevention and have paid less attention to the …

In observational epidemiologic studies, lower blood cholesterol is associated with a reduced
risk from coronary heart disease (CHD) throughout the normal range of cholesterol values …

The first in this series of historical reviews dealt with the pioneering animal model work of
Anitschkow, implicating blood cholesterol in the pathogenesis of atherosclerosis, and the …

High serum cholesterol is undoubtedly the knave of hearts in many developed and affluent
communities, where it interacts with endothelial injury to produce atherosclerosis. But, from …

Cholesterol and Atherosclerotic Cardiovascular Disease: A Lifelong Problem | Journal of the
American Heart Association Science Volunteer Warning signs SearchSearch Advanced Search …