Evaluation of the Cytotoxic Activity and Anti-Migratory Effect of Berberine–Phytantriol Liquid Crystalline Nanoparticle Formulation on Non-Small-Cell Lung Cancer In …

AM Alnuqaydan, AG Almutary, M Azam, B Manandhar… - Pharmaceutics, 2022 - mdpi.com
Non-small-cell lung cancer (NSCLC) is the most common form of lung cancer, which is a
leading cause of cancer-related deaths worldwide. Berberine is an isoquinoline alkaloid that …

Berberine-loaded liquid crystalline nanoparticles inhibit non-small cell lung cancer proliferation and migration in vitro

KR Paudel, M Mehta, GHS Yin, LL Yen… - … Science and Pollution …, 2022 - Springer
Non-small cell lung cancer (NSCLC) is reported to have a high incidence rate and is one of
the most prevalent types of cancer contributing towards 85% of all incidences of lung cancer …

[HTML][HTML] Cytotoxic mechanisms of berberine-phytantriol liquid crystalline nanoparticles against non-small-cell lung cancer

KR Paudel, B Manandhar, SK Singh, G Gupta… - EXCLI …, 2023 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of cancer-related deaths worldwide, with 1.79 million
reported deaths in the year 2020 alone (Thai et al., 2021). Non-small-cell lung cancer …

Rutin loaded liquid crystalline nanoparticles inhibit non-small cell lung cancer proliferation and migration in vitro

KR Paudel, R Wadhwa, XN Tew, NJX Lau… - Life sciences, 2021 - Elsevier
Non-small cell lung cancer (NSCLC) is one of the major causes of cancer-related mortality
globally. Despite the availability of therapeutic options, the improvement in patient survival is …

Berberine loaded liquid crystalline nanostructure inhibits cancer progression in adenocarcinomic human alveolar basal epithelial cells in vitro

M Mehta, V Malyla, KR Paudel… - Journal of food …, 2021 - Wiley Online Library
Metastasis represents the leading cause of death in lung cancer patients. C‐X‐C Motif
Chemokine Ligand 8 (CXCL‐8), Chemokine (C‐C motif) ligand 20 (CCL‐20) and heme …

Encapsulation of berberine into liquid crystalline nanoparticles to enhance its solubility and anticancer activity in MCF7 human breast cancer cells

YS Loo, T Madheswaran, R Rajendran… - Journal of Drug Delivery …, 2020 - Elsevier
Berberine, an isoquinoline alkaloid derived from Berberis vulgaris and plants of the
Ranunculaceae family, elicits a broad range of pharmacological effects, including anticancer …

Zerumbone-incorporated liquid crystalline nanoparticles inhibit proliferation and migration of non-small-cell lung cancer in vitro

B Manandhar, KR Paudel, DD Clarence… - Naunyn-Schmiedeberg's …, 2024 - Springer
Lung cancer is the second most prevalent type of cancer and is responsible for the highest
number of cancer-related deaths worldwide. Non-small-cell lung cancer (NSCLC) makes up …

Development and evaluation of long-circulating nanoparticles loaded with betulinic acid for improved anti-tumor efficacy

A Saneja, R Kumar, A Singh, RD Dubey… - International journal of …, 2017 - Elsevier
The clinical application of betulinic acid (BA), a natural pentacyclic triterpenoid with
promising antitumor activity, is hampered due to its extremely poor water solubility and …

Liquid crystalline assembly for potential combinatorial chemo–herbal drug delivery to lung cancer cells

HM Abdelaziz, AO Elzoghby, MW Helmy… - International journal …, 2019 - Taylor & Francis
Background Lung cancer is the most common cancer and the leading cause of total deaths
worldwide. Its classified into two major types including non-small cell lung carcinoma …

Enhancing the antitumor activity of berberine hydrochloride by solid lipid nanoparticle encapsulation

L Wang, H Li, S Wang, R Liu, Z Wu, C Wang, Y Wang… - Aaps Pharmscitech, 2014 - Springer
Berberine hydrochloride (BH) is an isoquinolin alkaloid with promising anticancer efficacies.
Nevertheless, further development and application of this compound had been hampered by …