[HTML][HTML] Live-Attenuated Salmonella-Based Oral Vaccine Candidates Expressing PCV2d Cap and Rep by Novel Expression Plasmids as a Vaccination Strategy for …
KKS Lloren, JH Lee - Vaccines, 2023 - mdpi.com
Oral vaccines are highly envisaged for veterinary applications due to their convenience and
ability to induce protective mucosal immunity as the first line of defense. The present …
ability to induce protective mucosal immunity as the first line of defense. The present …
Comparative immunogenic and immunoprotective activities of PCV2d Cap and Rep antigens delivered by an efficient eukaryotic expression system engineered into a …
KKS Lloren, C Sivasankar, JH Lee - Veterinary Microbiology, 2024 - Elsevier
Abstract Porcine circovirus type 2 (PCV2) stands as a predominant etiological agent in
porcine circovirus-associated diseases. To manage the spread of the disease, it is …
porcine circovirus-associated diseases. To manage the spread of the disease, it is …
Oral vaccination with attenuated Salmonella enterica serovar Typhimurium expressing Cap protein of PCV2 and its immunogenicity in mouse and swine models
XG Xu, HN Zhao, Q Zhang, L Ding, ZC Li, W Li… - Veterinary …, 2012 - Elsevier
Attenuated Salmonella enterica serovar Typhimurium (S. typhimurium) was selected as a
transgenic vehicle for the development of oral vaccines against Porcine circovirus type 2 …
transgenic vehicle for the development of oral vaccines against Porcine circovirus type 2 …
Oral vaccination with the porcine circovirus type 2 (PCV‐2) capsid protein expressed by Lactococcus lactis induces a specific immune response against PCV‐2 in …
L Wang, D Zhao, B Sun, M Yu, Y Wang… - Journal of applied …, 2020 - academic.oup.com
Aims Porcine circovirus type 2 (PCV2) can cause postweaning, multisystemic wasting
syndrome in pigs, which leads to enormous losses in the swine industry worldwide. Here, a …
syndrome in pigs, which leads to enormous losses in the swine industry worldwide. Here, a …
[HTML][HTML] Immunization of mice with delayed lysis Salmonella expressing PCV2b Cap protein enhanced mucosal and innate immunity and reduced viral load
G Zhang, Y Shen, Z Wang, G Hao, F Wang - Veterinary Vaccine, 2024 - Elsevier
ABSTRACT Porcine circovirus type 2 (PCV2) has been recognized as a critical pathogen
associated with numerous porcine circovirus-related diseases. Immunization is commonly …
associated with numerous porcine circovirus-related diseases. Immunization is commonly …
Construction of a Lactobacillus plantarum Strain Expressing the Capsid Protein of Porcine Circovirus Type 2d (PCV2d) as an Oral Vaccine
YH Tseng, CC Hsieh, TY Kuo, JR Liu, TY Hsu… - Indian journal of …, 2019 - Springer
Abstract Porcine circovirus type 2 (PCV2) is a pathogenic virus that causes high rates of
porcine death, resulting in severe economic losses to the swine industry. In recent years, the …
porcine death, resulting in severe economic losses to the swine industry. In recent years, the …
Live attenuated Salmonella enterica serovar Choleraesuis vector delivering a virus-like particles induces a protective immune response against porcine circovirus …
Y Li, Y Sun, Y Zhang, S Wang, H Shi - Vaccine, 2022 - Elsevier
The virus-like particles (VLPs) of porcine circovirus type 2 (PCV2) is an attractive vaccine
candidate that retains the natural conformation of the virion but lacks the viral genome to …
candidate that retains the natural conformation of the virion but lacks the viral genome to …
[HTML][HTML] Surface Display of porcine circovirus type 2 antigen protein cap on the spores of bacillus subtilis 168: An effective mucosal vaccine candidate
W Li, J Li, X Dai, M Liu, A Khalique, Z Wang… - Frontiers in …, 2022 - frontiersin.org
The oral mucosal vaccine has great potential in preventing a series of diseases caused by
porcine circovirus type 2 (PCV2) infection. This study constructed a recombinant Bacillus …
porcine circovirus type 2 (PCV2) infection. This study constructed a recombinant Bacillus …
Expression of the capsid protein of porcine circovirus type 2 in Lactococcus lactis for oral vaccination
K Wang, L Huang, J Kong, X Zhang - Journal of virological methods, 2008 - Elsevier
Diseases associated with porcine circovirus type 2 (PCV2) infections are becoming a major
problem for the swine industry worldwide. The capsid protein (Cap) of PCV2 is an antigen …
problem for the swine industry worldwide. The capsid protein (Cap) of PCV2 is an antigen …
The optimized capsid gene of porcine circovirus type 2 expressed in yeast forms virus-like particles and elicits antibody responses in mice fed with recombinant yeast …
SA Bucarey, J Noriega, P Reyes, C Tapia, L Sáenz… - Vaccine, 2009 - Elsevier
Porcine circovirus type 2 (PCV2)-associated diseases are considered to be the biggest
problem for the worldwide swine industry. The PCV2 capsid protein (Cap) is an important …
problem for the worldwide swine industry. The PCV2 capsid protein (Cap) is an important …
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