Sažetak Melatonin is a hormone that has many body functions and, for several decades, its
antioxidant potential has been increasingly talked about. There is a relationship between …

Many are the diseases which course with free radical formation. These disorders cover a
great range of fields such as neurodegenerative, immune, inflammatory and mitochondrial …

Melatonin is an endogenous hormone derived from tryptophan that is mainly released from
the pineal gland in the dark. Melatonin regulates many biological functions such as sleep …

In recent years, relationship between free radicals and oxidative stress with aging, cancer,
atherosclerosis, neurodegenerative disorders, diabetes, and inflammatory diseases became …

Melatonin acts classically through the widely expressed G protein-coupled membrane
receptors MT1 and MT2, respectively. The functional role of the MT receptors is not fully …

This brief resume enumerates the multiple actions of melatonin as an antioxidant. This
indoleamine is produced in the vertebrate pineal gland, the retina and possibly some other …

Over three centuries ago, the French philosopher René Descartes described the pineal
gland as “the seat of the soul.” However, it was not until the late 1950s that the chemical …

This review aims at describing the beneficial properties of melatonin related to its antioxidant
effects. Oxidative stress, ie, an imbalance between the production of reactive oxygen …

Neurodegeneration is the hallmark of many chronic progressive neurogical disorders
characterized by specific clinical, morphological and biochemical features. Central nervous …

The fact that the full extent of the function of the pineal gland has not yet been elucidated,
has stimulated melatonin research worldwide. This review introduces melatonin's …