Rosmarinic acid potentiates and detoxifies tacrine in combination for Alzheimer's disease

M Yang, X Zhang, O Qiao, H Ji, Y Zhang, X Han… - Phytomedicine, 2023 - Elsevier
Background There is no doubt that Alzheimer's disease (AD) is one of the greatest threats
facing mankind today. Within the next few decades, Acetylcholinesterase inhibitors (AChEIs) …

Alpinia oxyphylla–Schisandra chinensis Herb Pair Alleviates Amyloid-β Induced Cognitive Deficits via PI3K/Akt/Gsk-3β/CREB Pathway

Y Qi, H Jing, X Cheng, T Yan, F Xiao, B Wu, K Bi… - NeuroMolecular …, 2020 - Springer
Abstract Alzheimer's disease (AD), one of the most common neurodegenerative diseases,
threatens people's health. Based on the theory of traditional Chinese medicine (TCM) …

Chinese herbal extracts exert neuroprotective effect in Alzheimer's disease mouse through the dopaminergic synapse/apoptosis signaling pathway

Q Huang, C Zhang, S Qu, S Dong, Q Ma… - Frontiers in …, 2022 - frontiersin.org
Background: Alzheimer's disease (AD) as an age-related, irreversible neurodegenerative
disease, characterized by cognitive dysfunction, has become progressively serious with a …

Patchouli alcohol ameliorates the learning and memory impairments in an animal model of Alzheimer's disease via modulating SIRT1

QQ Xu, ZR Su, Z Hu, W Yang, YF Xian, ZX Lin - Phytomedicine, 2022 - Elsevier
Background Alzheimer's disease (AD) is one of the most prevalent neurodegenerative
diseases. Patchouli alcohol (PA), a major active ingredient isolated from Pogostemonis …

Integrating network pharmacology, UPLC-Q–TOF–MS and molecular docking to investigate the effect and mechanism of Chuanxiong Renshen decoction against …

ZJ Shen, YB Fu, JL Hou, LN Lin, XY Wang, CY Li… - Chinese Medicine, 2022 - Springer
Abstract Background and aim Chuanxiong Renshen decoction (CRD) is a traditional
Chinese medicine compound used to treat Alzheimer's disease (AD). However, the effects …

Acteoside ameliorates learning and memory impairment in APP/PS1 transgenic mice by increasing Aβ degradation and inhibiting tau hyperphosphorylation

L Gao, D Wang, J Ren, X Tan, J Chen… - Phytotherapy …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disease. Senile plaques and intracellular
neurofibrillary tangles are pathological hallmarks of AD. Recent studies have described the …

[HTML][HTML] Ameliorating effect of Alpinia oxyphylla—Schisandra chinensis herb pair on cognitive impairment in a mouse model of Alzheimer's disease

M Wang, W Bi, K Fan, T Li, T Yan, F Xiao, B He… - Biomedicine & …, 2018 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia. In our previous study, we
found both Alpinia oxyphylla and Schisandra chinensis can improve the cognitive function of …

Huatuo Zaizao pill ameliorates cognitive impairment of APP/PS1 transgenic mice by improving synaptic plasticity and reducing Aβ deposition

JH Zhang, LJ Yu, H Yang, Z Hui, S Jiang… - … and alternative medicine, 2018 - Springer
Background It is well known that Alzheimer's disease (AD) is a progressive
neurodegenerative disease characterized by memory deficits and cognitive decline. Amyloid …

Effects of huannao yicong recipe extract on the learning and memory and related factors of Abeta generation in the brain of APP transgenic mice

H Li, MF Liu, JG Liu, LT Liu, J Guan, LL Cai… - … Zhong xi yi jie he za …, 2013 - europepmc.org
Objective To study the effects of Huannao Yicong Recipe (HNYCR) extract on the learning
and memory ability, and the expressions of amyloid precursor protein (APP), beta-site APP …

Protocatechuic acid improves cognitive deficits and attenuates amyloid deposits, inflammatory response in aged AβPP/PS1 double transgenic mice

Y Song, T Cui, N Xie, X Zhang, Z Qian, J Liu - International …, 2014 - Elsevier
Protocatechuic acid (PCA), a phenolic compound of Radix Salviae Miltiorrhizae (RSM), has
been found to have a protective effect on improving cognitive deficits in STZ-induced AD …