[HTML][HTML] Neoadjuvant cemiplimab for stage II to IV cutaneous squamous-cell carcinoma

ND Gross, DM Miller, NI Khushalani… - … England Journal of …, 2022 - Mass Medical Soc
Background In a pilot study involving patients with cutaneous squamous-cell carcinoma, a
high percentage of patients had a pathological complete response with the use of two doses …

Cemiplimab in locally advanced cutaneous squamous cell carcinoma: results from an open-label, phase 2, single-arm trial

MR Migden, NI Khushalani, ALS Chang… - The lancet …, 2020 - thelancet.com
Background Cemiplimab has shown substantial antitumour activity in patients with
metastatic cutaneous squamous cell carcinoma. Patients with locally advanced cutaneous …

Cemiplimab for locally advanced and metastatic cutaneous squamous-cell carcinomas: real-life experience from the French CAREPI study group

C Hober, L Fredeau, A Pham-Ledard, M Boubaya… - Cancers, 2021 - mdpi.com
Simple Summary Prognosis of advanced cutaneous squamous-cell carcinoma (CSCC) is
poor. Recent clinical trials have shown that immunotherapy achieves significantly improved …

Phase II study of cemiplimab in patients (pts) with advanced cutaneous squamous cell carcinoma (CSCC): Longer follow-up.

D Rischin, NI Khushalani, CD Schmults, AD Guminski… - 2020 - ascopubs.org
10018 Background: Cemiplimab monotherapy achieves clinically meaningful activity in pts
with advanced CSCC (metastatic [mCSCC] or locally advanced [laCSCC] not amenable to …

Comparative efficacy of cemiplimab versus other systemic treatments for advanced cutaneous squamous cell carcinoma

S Keeping, Y Xu, CI Chen, S Cope, A Mojebi… - Future …, 2021 - Taylor & Francis
Aim: To estimate the comparative efficacy of cemiplimab, a programmed cell death protein 1
inhibitor, versus EGFR inhibitors, pembrolizumab and platinum-based chemotherapy in …

[HTML][HTML] Real world data of cemiplimab in locally advanced and metastatic cutaneous squamous cell carcinoma

A Baggi, P Quaglino, M Rubatto, R Depenni… - European Journal of …, 2021 - Elsevier
Background Cutaneous squamous cell carcinoma (cSCC) has an overall favourable
outcome, except for patients with an advanced stage disease. The programmed death …

Cemiplimab: a review in advanced cutaneous squamous cell carcinoma

A Lee, S Duggan, ED Deeks - Drugs, 2020 - Springer
Cemiplimab (Libtayo®) is an antibody immunotherapy that stimulates an anti-cancer
response via programmed cell death protein-1 (PD-1) blockade. It is the first approved …

Clinical outcomes among unresectable, locally advanced, and metastatic cutaneous squamous cell carcinoma patients treated with systemic therapy

CL Cowey, NJ Robert, JL Espirito, K Davies… - Cancer …, 2020 - Wiley Online Library
Prior studies of conventional chemotherapy or epidermal growth factor receptor inhibitors for
advanced (ie, locally advanced cutaneous squamous cell carcinoma [laCSCC] or metastatic …

[HTML][HTML] European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma: Part 2. Treatment–Update 2023

AJ Stratigos, C Garbe, C Dessinioti, C Lebbe… - European Journal of …, 2023 - Elsevier
In order to update recommendations on treatment, supportive care, education, and follow-up
of patients with invasive cutaneous squamous cell carcinoma (cSCC), a multidisciplinary …

PD-1 blockade with cemiplimab in advanced cutaneous squamous-cell carcinoma

MR Migden, D Rischin, CD Schmults… - … England Journal of …, 2018 - Mass Medical Soc
Background No systemic therapies have been approved for the treatment of advanced
cutaneous squamous-cell carcinoma. This cancer may be responsive to immune therapy …