Glucocorticoids (GCs) are potent immune‐modulating drugs with significant side effects,
including glucocorticoid‐induced osteoporosis (GIO). GCs directly induce osteoblast and …

Postmenopausal osteoporosis is a common bone metabolic disease, and gut microbiota
(GM) imbalance plays an important role in the development of metabolic bone disease …

A eubiotic microbiota influences many physiological processes in the metazoan host,
including development and intestinal homeostasis. Here, we have shown that the intestinal …

Osteonecrosis of the femoral head (ONFH) commonly occurs after glucocorticoid (GC)
therapy. The gut microbiota (GM) participates in regulating host health, and its composition …

Objectives Osteoporosis is a common bone disease in the elderly mainly regulated by
osteoblasts (OBs) and osteoclasts (OCs). The gut microbiota has been recognized as an …

Background Osteoporosis (OP) is a systemic metabolic bone disease characterized by
decreased bone mass and destruction of bone microstructure, which tends to result in …

Aims The effect of the gut microbiota (GM) and its metabolite on bone health is termed the
gut-bone axis. Multiple studies have elucidated the mechanisms but findings vary greatly. A …

Background With increasing knowledge about the gut–bone axis, more studies for
treatments based on the regulation of postmenopausal osteoporosis by gut microbes are …

Since glucocorticoids remain an effective therapeutic option for the treatment of many
inflammatory and autoimmune diseases, glucocorticoid-induced osteoporosis is the most …

The gut microbiota modulates host metabolism and development of immune status. Here we
show that the gut microbiota is also a major regulator of bone mass in mice. Germ‐free (GF) …