The rutin/β-cyclodextrin interactions in fully aqueous solution: spectroscopic studies and biological assays

ML Calabro, S Tommasini, P Donato… - … of pharmaceutical and …, 2005 - Elsevier
In the present work the feasibility of β-cyclodextrin complexation was explored, as a tool for
improving the aqueous solubility and antioxidant efficacy of rutin. By means of 1H NMR, UV …

Complex of rutin with β-cyclodextrin as potential delivery system

M Paczkowska, M Mizera, H Piotrowska… - PLoS …, 2015 - journals.plos.org
This study aimed to obtain and characterize an RU-β-CD complex in the context of
investigating the possibility of changes in the solubility, stability, antioxidative and …

Enhencemnet of solubility and photostability of rutin by complexation with β-cyclodextrin and (2-hydroxypropyl)-β-cyclodextrin

IM Savic, IM Savic-Gajic, VD Nikolic, LB Nikolic… - Journal of Inclusion …, 2016 - Springer
Rutin is a flavonoid and has found a wide application in the treatment of various chronic
diseases such as cancer, diabetes, hypertension and hypercholesterolemia. The …

An investigation into the supramolecular structure, solubility, stability and antioxidant activity of rutin/cyclodextrin inclusion complex

TA Nguyen, B Liu, J Zhao, DS Thomas, JM Hook - Food chemistry, 2013 - Elsevier
The formation of supramolecular inclusion complexes between rutin and four cyclodextrins,
namely β-cyclodextrin (β-CD),(2-hydroxypropyl)-α-cyclodextrin (HP-α-CD),(2-hydroxypropyl) …

The enhancement of isoflavones water solubility by complexation with modified cyclodextrins: a spectroscopic investigation with implications in the pharmaceutical …

R Stancanelli, A Mazzaglia, S Tommasini… - … of pharmaceutical and …, 2007 - Elsevier
The improvement of isoflavones bioavailability by complexation with chemically modified
cyclodextrins (CyDs) has been exploited to analyse the drug/macrocycle binding affinity by a …

Improvement of solubility and oral bioavailability of rutin by complexation with 2-hydroxypropyl-β-cyclodextrin

K Miyake, H Arima, F Hirayama… - Pharmaceutical …, 2000 - Taylor & Francis
The object of this study was to enhance the solubility, dissolution rate, and oral
bioavailability of rutin by complexation with 2-hydroxypropyl-β-cyclodextrin (HP-β-CyD). The …

Host–guest interaction study of resveratrol with natural and modified cyclodextrins

V Bertacche, N Lorenzi, D Nava, E Pini… - Journal of inclusion …, 2006 - Springer
The aim of this work is to increase the stability and water solubility of resveratrol by
complexation with different cyclodextrins. Furthermore, physical–chemical properties of each …

Inclusion complexes of rosmarinic acid and cyclodextrins: stoichiometry, association constants, and antioxidant potential

B Medronho, A JM Valente, P Costa… - Colloid and Polymer …, 2014 - Springer
The interaction between β-cyclodextrin (β-CD) and the polyphenol rosmarinic acid (RA) is
here reported by 1 H NMR titration experiments. The formation of an aqueous soluble …

Determination of the formation constant for the inclusion complex between rutin and methyl-β-cyclodextrin

S Letellier, B Maupas, JP Gramond, F Guyon… - Analytica chimica …, 1995 - Elsevier
The interaction of rutin and methyl-β-cyclodextrin in aqueous solution was studied by UV,
fluorescence spectroscopy and reversed-phase liquid chromatography. Free solution …

The inclusion complex of rosmarinic acid into beta-cyclodextrin: A thermodynamic and structural analysis by NMR and capillary electrophoresis

A Aksamija, A Polidori, R Plasson, O Dangles… - Food Chemistry, 2016 - Elsevier
This work focuses on the characterization of the rosmarinic acid (RA)-β-cyclodextrin (CD)
complex in aqueous solution by 1 H NMR (1D-and 2D-ROESY), completed with studies by …