Interventions for liver grafts with moderate macrovesicular steatosis have been important in
enlarging donor pools. Here, we tested a high-fat and cholesterol (HFC) diet to create a …

Macrovesicular steatosis in greater than 30% of hepatocytes is a significant risk factor for
primary graft nonfunction due to increased sensitivity to ischemia reperfusion (I/R) injury …

The current drastic shortage of donor organs has led to acceptance of extended-criteria
donors for transplantation, despite higher risk of primary nonfunction. Here, we report the …

Chronic shortage of donor organs has led to acceptance of steatotic livers as grafts,
although there is a higher risk of primary graft dysfunction. We herein report the beneficial …

Background/Aims: The incidence of steatosis in livers retrieved for organ transplantation is
up to 30%. Due to the shortage of donor organs, many of these livers are accepted for …

Liver steatosis is a leading cause of graft disposal in liver transplantation, though the degree
of steatosis is often the single factor determining acceptability of the graft. We investigated …

Liver allograft steatosis is a significant risk factor for postoperative graft dysfunction and has
been associated with inferior patient and graft survival, particularly in the case of moderate …

Background. Fatty livers are more prone to primary nonfunction after transplantation. It is
known that cell injury is strongly associated with alterations in the content and composition …

Short-term weight reduction (SWR) programs have been demonstrated to ameliorate liver
steatosis, transforming marginal donors into viable candidates for living donor liver …

The shortage of donor livers has led to an increased use of organs from expanded criteria
donors. Included are livers with steatosis, a metabolic abnormality that increases the …