Excellent T-cell reconstitution and survival depend on low ATG exposure after pediatric cord blood transplantation
R Admiraal, CA Lindemans… - Blood, The Journal …, 2016 - ashpublications.org
Successful immune reconstitution (IR) is associated with improved outcomes following
pediatric cord blood transplantation (CBT). Usage and timing of anti–thymocyte globulin …
pediatric cord blood transplantation (CBT). Usage and timing of anti–thymocyte globulin …
[HTML][HTML] Early and long-term impaired T lymphocyte immune reconstitution after cord blood transplantation with antithymocyte globulin
N Castillo, I García-Cadenas, P Barba, C Canals… - Biology of Blood and …, 2017 - Elsevier
Immune reconstitution is crucial to the success of allogeneic hematopoietic stem cell
transplantation. Umbilical cord blood transplantation (UCBT) has been associated with …
transplantation. Umbilical cord blood transplantation (UCBT) has been associated with …
[HTML][HTML] Immune reconstitution and outcomes after conditioning with anti-thymocyte-globulin in unrelated cord blood transplantation; the good, the bad, and the ugly
C De Koning, R Admiraal, S Nierkens… - Stem Cell …, 2017 - ncbi.nlm.nih.gov
Unrelated umbilical cord blood transplantation (UCBT) exhibits a low risk of graft-versus-
host-disease (GvHD) and has unique potent anti-virus and anti-leukemia effects. Anti …
host-disease (GvHD) and has unique potent anti-virus and anti-leukemia effects. Anti …
Impact of thymoglobulin prior to pediatric unrelated umbilical cord blood transplantation on immune reconstitution and clinical outcome
CA Lindemans, R Chiesa, PJ Amrolia… - Blood, The Journal …, 2014 - ashpublications.org
In vivo T-cell depletion might contribute to the delayed immune reconstitution observed after
unrelated umbilical cord blood transplantation (UCBT). We studied the impact of early, late …
unrelated umbilical cord blood transplantation (UCBT). We studied the impact of early, late …
Robust CD4+ T-cell recovery in adults transplanted with cord blood and no antithymocyte globulin
Quality of immune reconstitution after cord blood transplantation (CBT) without
antithymocyte globulin (ATG) in adults is not established. We analyzed immune recovery in …
antithymocyte globulin (ATG) in adults is not established. We analyzed immune recovery in …
Immune reconstitution after unrelated cord blood transplantation
P Szabolcs, D Niedzwiecki - Cytotherapy, 2007 - Taylor & Francis
Over the past years unrelated cord blood transplant (UCBT) has emerged as an effective
alternative to unrelated donor blood and marrow transplantation. However, despite several …
alternative to unrelated donor blood and marrow transplantation. However, despite several …
Omission of in vivo T‐cell depletion promotes rapid expansion of naïve CD4+ cord blood lymphocytes and restores adaptive immunity within 2 months after …
R Chiesa, K Gilmour, W Qasim, S Adams… - British journal of …, 2012 - Wiley Online Library
Umbilical cord blood transplant (UCBT) is associated with impaired early immune
reconstitution. This might be explained by a lower T‐cell dose infused, the naivety of cord …
reconstitution. This might be explained by a lower T‐cell dose infused, the naivety of cord …
Association between anti-thymocyte globulin exposure and CD4+ immune reconstitution in paediatric haemopoietic cell transplantation: a multicentre, retrospective …
R Admiraal, C van Kesteren… - The Lancet …, 2015 - thelancet.com
Background Anti-thymocyte globulin (ATG) was introduced into the conditioning regimen in
haemopoietic cell transplantation (HCT) to prevent graft-versus-host-disease (GvHD) and …
haemopoietic cell transplantation (HCT) to prevent graft-versus-host-disease (GvHD) and …
Impact of ATG-containing reduced-intensity conditioning after single-or double-unit allogeneic cord blood transplantation
L Pascal, L Tucunduva, A Ruggeri… - Blood, The Journal …, 2015 - ashpublications.org
We analyzed 661 adult patients who underwent single-unit (n= 226) or double-unit (n= 435)
unrelated cord blood transplantation (UCBT) following a reduced-intensity conditioning …
unrelated cord blood transplantation (UCBT) following a reduced-intensity conditioning …
[HTML][HTML] Serious infection risk and immune recovery after double-unit cord blood transplantation without antithymocyte globulin
C Sauter, M Abboud, X Jia, G Heller… - Biology of Blood and …, 2011 - Elsevier
Factors contributing to infection risk after cord blood transplantation (CBT) include the use of
anti-thymocyte globulin (ATG), prolonged neutropenia, and failure to transfer immunity. In …
anti-thymocyte globulin (ATG), prolonged neutropenia, and failure to transfer immunity. In …