Exploring the Pathophysiology of Long COVID: The Central Role of Low-Grade Inflammation and Multisystem Involvement

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2024 - mdpi.com
Long COVID (LC), also referred to as Post COVID-19 Condition, Post-Acute Sequelae of
SARS-CoV-2 Infection (PASC), and other terms, represents a complex multisystem disease …

Pathophysiology and mechanism of long COVID: a comprehensive review

D Castanares-Zapatero, P Chalon, L Kohn… - Annals of …, 2022 - Taylor & Francis
Background After almost 2 years of fighting against SARS-CoV-2 pandemic, the number of
patients enduring persistent symptoms long after acute infection is a matter of concern. This …

Long COVID: Clinical characteristics, proposed pathogenesis and potential therapeutic targets

G Kenny, L Townsend, S Savinelli… - Frontiers in Molecular …, 2023 - frontiersin.org
The emergence of persistent ill-health in the aftermath of SARS-CoV-2 infection has
presented significant challenges to patients, healthcare workers and researchers. Termed …

Pathophysiological, immunological, and inflammatory features of long COVID

K Bohmwald, B Diethelm-Varela… - Frontiers in …, 2024 - frontiersin.org
The COVID-19 pandemic continues to cause severe global disruption, resulting in significant
excess mortality, overwhelming healthcare systems, and imposing substantial social and …

Long COVID: molecular mechanisms and detection techniques

A Constantinescu-Bercu, A Lobiuc… - International Journal of …, 2023 - mdpi.com
Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), has
emerged as a significant health concern following the COVID-19 pandemic. Molecular …

[HTML][HTML] Unveiling the mysteries of long COVID syndrome: exploring the distinct tissue and organ pathologies linked to prolonged COVID-19 symptoms

FNU Sapna, FNU Deepa, FNU Sakshi, FNU Sonam… - Cureus, 2023 - ncbi.nlm.nih.gov
The ongoing battle against the coronavirus disease 2019 (COVID-19) pandemic has
encountered a complex aspect with the emergence of long COVID syndrome. There has …

Laboratory findings and biomarkers in Long COVID: what do we know so far? Insights into epidemiology, pathogenesis, therapeutic perspectives and challenges

D Tsilingiris, NG Vallianou, I Karampela… - International Journal of …, 2023 - mdpi.com
Long COVID (LC) encompasses a constellation of long-term symptoms experienced by at
least 10% of people after the initial SARS-CoV-2 infection, and so far it has affected about 65 …

The knowns and unknowns of long COVID-19: from mechanisms to therapeutical approaches

R Gheorghita, I Soldanescu, A Lobiuc… - Frontiers in …, 2024 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has been
defined as the greatest global health and socioeconomic crisis of modern times. While most …

[PDF][PDF] Pathophysiological mechanisms of disease severity in COVID-19: An update

MHB Siam, SMDM Abedin, A Ahmed… - J. Adv. Biotechnol …, 2020 - researchgate.net
The pandemic of COVID-19 has created a confounding global health crisis with more than
25 million cases and 870,000 deaths worldwide. The novel coronavirus, SARS-CoV-2 …

Challenges and opportunities in long COVID research

RE Hamlin, CA Blish - Immunity, 2024 - cell.com
Long COVID (LC) is a condition in which patients do not fully recover from the initial SARS-
CoV-2 infection but rather have persistent or new symptoms for months to years following …