The origin and function of CD20+ T cells are poorly understood. Here, we characterized
CD20+ T cells in mice and humans and investigated how they are affected by anti-CD20 …

With the discovery that the highly effective anti-CD20 antibody therapies developed to
deplete CD20+ B cells deplete CD20+ T cells equally well, a great interest in the biological …

Introduction Although CD20 is classically a B cell marker, in the last three decades, dim
expression has been noted on a subset of T cells as well that has been independently …

CD11c+ dendritic cells (DCs) are a prominent component of CNS infiltrates in mice with
experimental autoimmune encephalomyelitis. However, their role in immunopathogenesis is …

Inflammation contributes to the development and perpetuation of several disorders and T
lymphocytes orchestrate the inflammatory immune response. Although the role of T cells in …

Tc17 cells-a subset of CD8+ T cells-have recently been identified that are characterized by
the production of interleukin (IL)-17. Cytokines IL-6 and transforming growth factor-beta 1 …

CD20 antibody depletion of B lymphocytes effectively ameliorates multiple T cell-mediated
autoimmune diseases through mechanisms that remain unclear. To address this, a mouse …

The importance of CD8 T cells in the pathogenesis of organ-specific autoimmune diseases
has not previously been well recognized. Recent evidence, however, indicates that …

CD6 was established as a marker of T cells more than three decades ago, and recent
studies have identified CD6 as a risk gene for multiple sclerosis (MS), a disease in which …

CD8 T cells play crucial roles in immune surveillance and defense against infections and
cancer. After encountering antigenic stimulation, naïve CD8 T cells differentiate and acquire …