Contribution of T-and B-cell intrinsic toll-like receptors to the adaptive immune response in viral infectious diseases

E Zhang, Z Ma, M Lu - Cellular and Molecular Life Sciences, 2022 - Springer
Toll-like receptors (TLRs) comprise a class of highly conserved molecules that recognize
pathogen-associated molecular patterns and play a vital role in host defense against …

Toll-like receptors and innate immunity

H Kumar, T Kawai, S Akira - Biochemical and biophysical research …, 2009 - Elsevier
Toll-like receptors (TLRs) are evolutionarily conserved innate receptors expressed in
various immune and non-immune cells of the mammalian host. TLRs play a crucial role in …

Toll-like receptors regulation of viral infection and disease

JM Thompson, A Iwasaki - Advanced drug delivery reviews, 2008 - Elsevier
In recent years, it has become increasingly evident that mammalian Toll-like receptors
(TLRs) play a critical role in determining the outcome of virus infection. TLRs have evolved …

Recent insights into the role of Toll-like receptors in viral infection

M Carty, AG Bowie - Clinical & Experimental Immunology, 2010 - academic.oup.com
Toll-like receptors (TLRs) have a central role in innate immunity as they detect conserved
pathogen-associated molecular patterns (PAMPs) on a range of microbes, including viruses …

Expression and function of Toll-like receptors in T lymphocytes

D Kabelitz - Current opinion in immunology, 2007 - Elsevier
Toll-like receptors (TLRs) are widely expressed in the innate immune system. They
recognize conserved microbial ligands such as bacterial lipopolysaccharide, lipopeptides or …

Toll-like receptors in human infectious diseases

S Barrera, M Alemán, MC Sasiain - Current pharmaceutical …, 2006 - ingentaconnect.com
Toll-like receptors (TLRs) have emerged as critical players in immunity. They are capable of
sensing organisms ranging from protozoa to bacteria, fungi or viruses upon detection of the …

[PDF][PDF] Direct and indirect role of Toll-like receptors in T cell mediated immunity

D Xu, H Liu, M Komai-Koma - Cell Mol Immunol, 2004 - researchgate.net
Toll-like receptors (TLR) are pathogen-associated molecular patterns (PAMPs) recognition
receptors that play an important role in protective immunity against infection and …

Toll-like receptors in antiviral innate immunity

SN Lester, K Li - Journal of molecular biology, 2014 - Elsevier
Toll-like receptors (TLRs) are fundamental sensor molecules of the host innate immune
system, which detect conserved molecular signatures of a wide range of microbial …

Toll-like receptor signaling and its role in cell-mediated immunity

T Duan, Y Du, C Xing, HY Wang, RF Wang - Frontiers in Immunology, 2022 - frontiersin.org
Innate immunity is the first defense system against invading pathogens. Toll-like receptors
(TLRs) are well-defined pattern recognition receptors responsible for pathogen recognition …

Toll-like receptors: key players in antiviral immunity

N Arpaia, GM Barton - Current opinion in virology, 2011 - Elsevier
TLRs are a family of innate receptors whose specificities are predetermined in the germline.
Therefore, TLRs have evolved to recognize conserved features of microbes. Viruses …