Thin-walled microvessels in human coronary atherosclerotic plaques show incomplete endothelial junctions: relevance of compromised structural integrity for …

JC Sluimer, FD Kolodgie, APJJ Bijnens… - Journal of the American …, 2009 - jacc.org
Objectives: This study sought to examine the ultrastructure of microvessels in normal and
atherosclerotic coronary arteries and its association with plaque phenotype. Background …

Plaque neovascularization is increased in ruptured atherosclerotic lesions of human aorta: implications for plaque vulnerability

PR Moreno, KR Purushothaman, V Fuster… - Circulation, 2004 - Am Heart Assoc
Background—Growth of atherosclerotic plaques is accompanied by neovascularization from
vasa vasorum microvessels extending through the tunica media into the base of the plaque …

Leucocyte recruitment in rupture prone regions of lipid-rich plaques: a prominent role for neovascularization?

OJ de Boer, AC Van Der Wal, P Teeling… - Cardiovascular …, 1999 - academic.oup.com
Objective: Microvessels in atherosclerotic plaques provide an alternative pathway for the
recruitment of leucocytes in the lesions. The present study was designed to investigate the …

Microemboli and microvascular obstruction in acute coronary thrombosis and sudden coronary death: relation to epicardial plaque histopathology

RS Schwartz, A Burke, A Farb, D Kaye… - Journal of the American …, 2009 - jacc.org
Objectives: This study examined myocardial microvascular emboli and obstruction, and
related these to plaque in the epicardial coronary arteries supplying the affected …

Coronary microvascular dysfunction: mechanisms and functional assessment

PG Camici, G d'Amati, O Rimoldi - Nature Reviews Cardiology, 2015 - nature.com
Obstructive disease of the epicardial coronary arteries was recognized as the cause of
angina pectoris> 2 centuries ago, and sudden thrombotic occlusion of an epicardial …

Coronary “microvascular dysfunction”: evolving understanding of pathophysiology, clinical implications, and potential therapeutics

CY Kei, K Singh, RF Dautov, TH Nguyen… - International Journal of …, 2023 - mdpi.com
Until recently, it has been generally held that stable angina pectoris (SAP) primarily reflects
the presence of epicardial coronary artery stenoses due to atheromatous plaque (s), while …

A review of methods for assessment of coronary microvascular disease in both clinical and experimental settings

AR Pries, H Habazettl, G Ambrosio… - Cardiovascular …, 2008 - academic.oup.com
Obstructive disease of the large coronary arteries is the prominent cause for angina pectoris.
However, angina may also occur in the absence of significant coronary atherosclerosis or …

Relation of arterial geometry to luminal narrowing and histologic markers for plaque vulnerability: the remodeling paradox

G Pasterkamp, AH Schoneveld, AC van der Wal… - Journal of the American …, 1998 - jacc.org
Objective. To relate local arterial geometry with markers that are thought to be related to
plaque rupture. Background. Plaque rupture often occurs at sites with minor luminal stenosis …

Elevated levels of VE-cadherin-positive endothelial microparticles in patients with type 2 diabetes mellitus and coronary artery disease

H Koga, S Sugiyama, K Kugiyama, K Watanabe… - Journal of the American …, 2005 - jacc.org
Objectives: The purpose of this study was to examine whether CD144-EMP (endothelium-
derived microparticles) is useful as a specific marker of endothelial cell (EC) dysfunction and …

Angiogenesis in human coronary atherosclerotic plaques.

ER O'Brien, MR Garvin, R Dev, DK Stewart… - The American journal …, 1994 - ncbi.nlm.nih.gov
Neovascularization in the walls of coronary arteries is associated with the presence of
atherosclerotic plaque. The mechanisms responsible for the formation of these intraplaque …