Background Cardiac arrest (CA) has been a leading cause of death for many decades.
Despite years of research, we still do not understand how each organ responds to the …

Cardiac arrest (CA) is a leading cause of death and there is a necessity for animal models
that accurately represent human injury severity. We evaluated a rat model of severe CA …

Background Out-of-hospital cardiac arrest (OHCA) is a leading cause of death. Even if
successfully resuscitated, mortality remains high due to ischemic and reperfusion injury (I/R) …

Cardiac arrest (CA) is not a uniform condition and its pathophysiology strongly depends on
its cause. In this work we have used a metabolomics approach to study the dynamic …

Acute kidney injury (AKI) is a systemic disease associated with widespread effects on distant
organs, including the heart. Normal cardiac function is dependent on constant ATP …

Background Cardiac arrest induces whole body ischemia, which causes damage to multiple
organs particularly the heart and the brain. There is clinical and preclinical evidence that …

Introduction Remote ischemic conditioning (RIC) is a maneuver by which short non-lethal
ischemic events are applied on distant organs or limbs to reduce ischemia and reperfusion …

The use of aggressive crystalloid resuscitation to treat hypoxemia, hypovolemia, and nutrient
deprivation promoted by massive blood loss may lead to the development of the blood …

Cardiac arrest is one of the major causes of death and disability. The aim of the study was to
identify dynamic time‐dependent metabolomic changes reflected in rat plasma induced by …

Background—Human myocardial metabolism has been incompletely characterized in the
setting of surgical cardioplegic arrest and ischemia/reperfusion. Furthermore, the effect of …