Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome

T Tamura, M Suzuki, K Hayashida… - Journal of Clinical …, 2020 - jstage.jst.go.jp
抄録 Oxidative stress plays a key role in the pathophysiology of post-cardiac arrest
syndrome. Molecular hydrogen reduces oxidative stress and exerts anti-inflammatory effects …

Hydrogen inhalation is superior to mild hypothermia for improving neurological outcome and survival in a cardiac arrest model of spontaneously hypertensive rat

G Chen, B Chen, C Dai, J Wang, J Wang, Y Huang… - Shock, 2018 - journals.lww.com
Background: Postcardiac arrest syndrome is the consequence of whole-body ischemia–
reperfusion events that lead to multiple organ failure and eventually to death. Recent animal …

Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation

K Kohama, H Yamashita, M Aoyama-Ishikawa… - Surgery, 2015 - Elsevier
Introduction Hemorrhagic shock followed by fluid resuscitation (HS/R) triggers an
inflammatory response and causes pulmonary inflammation that can lead to acute lung …

Hydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats

T Huo, Y Zeng, X Liu, L Sun, H Han, H Chen… - Anesthesia & …, 2014 - journals.lww.com
BACKGROUND: Sudden cardiac arrest is a leading cause of death worldwide. Three-fourths
of cardiac arrest patients die before hospital discharge or experience significant …

High concentration hydrogen mitigates sepsis-induced acute lung injury in mice by alleviating mitochondrial fission and dysfunction

N Zhao, R Sun, Y Cui, Y Song, W Ma, Y Li… - Journal of Personalized …, 2023 - mdpi.com
Background: Multiple organ failure (MOF) is the main cause of early death in septic shock.
Lungs are among the organs that are affected in MOF, resulting in acute lung injury. A large …

Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress

K Fukuda, S Asoh, M Ishikawa, Y Yamamoto… - Biochemical and …, 2007 - Elsevier
We have recently showed that molecular hydrogen has great potential for selectively
reducing cytotoxic reactive oxygen species, such as hydroxyl radicals, and that inhalation of …

Molecular hydrogen alleviates lung injury after traumatic brain injury: Pyroptosis and apoptosis

T Li, T Sun, YZ Wang, Q Wan, WZ Li… - European Journal of …, 2022 - Elsevier
Background Traumatic brain injury (TBI)-induced acute lung injury (ALI) is a critical
condition, and inflammation and apoptosis play essential roles. Molecular hydrogen (H 2) …

Molecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy

Y Cui, Y Li, S Meng, Y Song, K Xie - BMC anesthesiology, 2024 - Springer
Background Approximately 40 to 60% of patients with sepsis develop sepsis-induced
cardiomyopathy (SIC), which is associated with a substantial increase in mortality. We have …

H2 Gas Improves Functional Outcome After Cardiac Arrest to an Extent Comparable to Therapeutic Hypothermia in a Rat Model

K Hayashida, M Sano, N Kamimura… - Journal of the …, 2012 - Am Heart Assoc
Background All clinical and biological manifestations related to postcardiac arrest (CA)
syndrome are attributed to ischemia–reperfusion injury in various organs including brain …

[HTML][HTML] Hydrogen sulfide inhalation improves neurological outcome via NF-κB-mediated inflammatory pathway in a rat model of cardiac arrest and resuscitation

X Wei, B Zhang, Y Zhang, H Li, L Cheng… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: The effects of H 2 S on cerebral inflammatory reaction after cardiac arrest
(CA) and cardiopulmonary resuscitation (CPR) remain poorly understood. In this study, we …