Unraveling molecular and genetic insights into neurodegenerative diseases: Advances in understanding Alzheimer's, Parkinson's, and Huntington's diseases and …

AV Ciurea, AG Mohan, RA Covache-Busuioc… - International journal of …, 2023 - mdpi.com
Neurodegenerative diseases are, according to recent studies, one of the main causes of
disability and death worldwide. Interest in molecular genetics has started to experience …

Trends in the molecular pathogenesis and clinical therapeutics of common neurodegenerative disorders

YE Choonara, V Pillay, LC Du Toit, G Modi… - International journal of …, 2009 - mdpi.com
The term neurodegenerative disorders, encompasses a variety of underlying conditions,
sporadic and/or familial and are characterized by the persistent loss of neuronal subtypes …

Novel approaches for the treatment of Alzheimer's and Parkinson's disease

M Van Bulck, A Sierra-Magro, J Alarcon-Gil… - International journal of …, 2019 - mdpi.com
Neurodegenerative disorders affect around one billion people worldwide. They can arise
from a combination of genomic, epigenomic, metabolic, and environmental factors. Aging is …

Commonalities in biological pathways, genetics, and cellular mechanism between Alzheimer disease and other neurodegenerative diseases: an in silico-updated …

K Ahmad, M Hassan Baig, G Mushtaq… - Current Alzheimer …, 2017 - ingentaconnect.com
Background: Alzheimer's disease (AD) is the most common and well-studied
neurodegenerative disease (ND). Biological pathways, pathophysiology and genetics of AD …

[HTML][HTML] Emerging pathways to neurodegeneration: Dissecting the critical molecular mechanisms in Alzheimer's disease, Parkinson's disease

SH Tan, V Karri, NWR Tay, KH Chang, HY Ah… - Biomedicine & …, 2019 - Elsevier
Neurodegenerative diseases are usually sporadic in nature and commonly influenced by a
wide range of genetic, life style and environmental factors. A unifying feature of Alzheimer's …

Current concepts of neurodegenerative mechanisms in Alzheimer's disease

KB Magalingam, A Radhakrishnan… - BioMed research …, 2018 - Wiley Online Library
Neurodegenerative diseases are hereditary or sporadic conditions that result in the
progressive loss of the structure and function of neurons as well as neuronal death …

Neurodegenerative diseases: from molecular basis to therapy

L Agnello, M Ciaccio - International journal of molecular sciences, 2022 - mdpi.com
NDs represent a significant health problem worldwide, with an increasing incidence rate.
Although the exact pathogenesis of NDs remains unclear, a complex interaction among …

Pathogenesis of dementia

JW Błaszczyk - International Journal of Molecular Sciences, 2022 - mdpi.com
According to Alzheimer's Disease International, 55 million people worldwide are living with
dementia. Dementia is a disorder that manifests as a set of related symptoms, which usually …

Towards unveiling the genetics of neurodegenerative diseases

CM Lill, L Bertram - Seminars in neurology, 2011 - thieme-connect.com
In addition to sharing several clinical, pathologic, and molecular characteristics, many
neurodegenerative disorders show extensive familial histories suggesting a substantial …

Epigenetic modulation in Parkinson's disease and potential treatment therapies

AS Rathore, H Birla, SS Singh, W Zahra… - Neurochemical …, 2021 - Springer
In the recent past, huge emphasis has been given to the epigenetic alterations of the genes
responsible for the cause of neurological disorders. Earlier, the scientists believed somatic …