[HTML][HTML] Relationship between osteoporosis and osteoarthritis based on DNA methylation
Y Li, B Xie, Z Jiang, B Yuan - International journal of clinical and …, 2019 - ncbi.nlm.nih.gov
The aim of this study was to investigate the relationship between osteoporosis and
osteoarthritis by analyzing the DNA methylation in osteoporosis and osteoarthritis. The …
osteoarthritis by analyzing the DNA methylation in osteoporosis and osteoarthritis. The …
Genome‐wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis
J Delgado‐Calle, AF Fernández, J Sainz… - Arthritis & …, 2013 - Wiley Online Library
Objective To determine genome‐wide methylation profiles of bone from patients with hip
osteoarthritis (OA) and those with osteoporotic (OP) hip fractures. Methods Trabecular bone …
osteoarthritis (OA) and those with osteoporotic (OP) hip fractures. Methods Trabecular bone …
DNA methylation signatures of bone metabolism in osteoporosis and osteoarthritis aging-related diseases: an updated review
VV Visconti, I Cariati, S Fittipaldi, R Iundusi… - International Journal of …, 2021 - mdpi.com
DNA methylation is one of the most studied epigenetic mechanisms that play a pivotal role in
regulating gene expression. The epigenetic component is strongly involved in aging-bone …
regulating gene expression. The epigenetic component is strongly involved in aging-bone …
[HTML][HTML] DNA methylation in osteoarthritis: current status and therapeutic implications
A Miranda-Duarte - The open rheumatology journal, 2018 - ncbi.nlm.nih.gov
Background: Primary Osteoarthritis (OA) is a multifactorial disease in which genetic factors
are strongly associated with its development; however, recently it has been observed that …
are strongly associated with its development; however, recently it has been observed that …
Alterations in DNA methylation profiles in cancellous bone of postmenopausal women with osteoporosis
Y Zhou, L Yang, H Wang, X Chen, W Jiang… - FEBS Open …, 2020 - Wiley Online Library
Osteoporosis is characterized by systemic microarchitecture impairment and bone loss,
which ultimately lead to fragility fractures. This disease is most common in older people …
which ultimately lead to fragility fractures. This disease is most common in older people …
Alterations in DNA methylation machinery in a rat model of osteoarthritis of the hip
Y Kawarai, J Nakamura, S Hagiwara… - Journal of Orthopaedic …, 2024 - Springer
Background This study aimed to validate alterations in the gene expression of DNA
methylation-related enzymes and global methylation in the peripheral blood mononuclear …
methylation-related enzymes and global methylation in the peripheral blood mononuclear …
Analysis of methylation datasets identified significantly changed genes and functional pathways in osteoarthritis
B Han, Z Zheng, J Ren, W Qiu, X Li - Clinical Rheumatology, 2019 - Springer
Background Researches indicate that epigenetics was involved in osteoarthritis (OA). The
purpose of this study was to describe the alterations of DNA methylation in hip and knee OA …
purpose of this study was to describe the alterations of DNA methylation in hip and knee OA …
Identification of an epigenetic signature of osteoporosis in blood DNA of postmenopausal women
Osteoporosis is one of the most common age‐related progressive bone diseases in elderly
people. Approximately one in three women and one in five men are predisposed to …
people. Approximately one in three women and one in five men are predisposed to …
Identification of abnormally methylated–differentially expressed genes and pathways in osteoarthritis: a comprehensive bioinformatic study
L Zheng, W Chen, G Xian, B Pan, Y Ye, M Gu… - Clinical …, 2021 - Springer
Objectives To investigate abnormally methylated–differentially expressed genes (DEGs) and
their related pathways in osteoarthritis (OA) by comprehensive bioinformatic analysis …
their related pathways in osteoarthritis (OA) by comprehensive bioinformatic analysis …
The influence of DNA methylation on bone cells
S Reppe, H Datta, KM Gautvik - Current genomics, 2015 - ingentaconnect.com
DNA methylation in eukaryotes invokes heritable alterations of the of the cytosine base in
DNA without changing the underlying genomic DNA sequence. DNA methylationmay be …
DNA without changing the underlying genomic DNA sequence. DNA methylationmay be …