Cigarette smoke induced neural tube defects by down‐regulating noggin expression

C Yin, H Cai, D Yang, Y Jian, J Zhang… - Birth Defects …, 2021 - Wiley Online Library
Background Maternal smoking or passive smoking during gestation increases the risk of
congenital birth defects, including neural tube defects (NTDs). Cigarette smoke is a …

Nicotine exposure disrupts placental development via the Notch signaling pathway

QR Sun, DY Wu, JJ Zhang, LH Wu, X Zhang… - …, 2023 - rep.bioscientifica.com
In brief Normal gene expression during early embryonic development and in the placenta is
crucial for a successful pregnancy. Nicotine can disrupt normal gene expression during …

Maternal nicotine exposure induces congenital heart defects in the offspring of mice

ER Greco, A Engineer, T Saiyin, X Lu… - Journal of Cellular …, 2022 - Wiley Online Library
Maternal cigarette smoking is a risk factor for congenital heart defects (CHDs). Nicotine
replacement therapies are often offered to pregnant women following failed attempts of …

Maternal smoking, passive tobacco smoke, and neural tube defects

L Suarez, T Ramadhani, M Felkner… - … Research Part A …, 2011 - Wiley Online Library
BACKGROUND Although cigarette smoke is a well‐established toxin and harmful to the
developing embryo, the evidence for an independent effect on the occurrence of neural tube …

Impact of Prenatal Nicotine Exposure on Placental Function and Respiratory Neural Network Development

S Beltrán-Castillo, K Bravo, J Eugenín - Advances in Maternal-Fetal …, 2023 - Springer
Smoking during pregnancy is associated with multiple undesirable outcomes in infants, such
as low birth weight, increased neonatal morbidity and mortality, and catastrophic conditions …

Maternal passive smoking and the risk of neural tube defects: a case-control study in Shanxi province, China

ZW Li, JM Liu, AG Ren, L Zhang, ZY Guo… - … liu Xing Bing xue za zhi …, 2008 - europepmc.org
Objective To explore the relationship between maternal passive smoking during early
pregnancy and the risk of neural tube defects (NTDs). Methods Data was derived from a …

[HTML][HTML] Prenatal NO2 exposure and neurodevelopmental disorders in offspring mice: Transcriptomics reveals sex-dependent changes in cerebral gene expression

W Yan, H Yue, X Ji, G Li, N Sang - Environment international, 2020 - Elsevier
Background Early-life exposure to nitrogen dioxide (NO 2) is associated with an increased
risk of developing a neurodevelopmental disorder during childhood or later in life …

[HTML][HTML] Impact of maternal cigarette smoke exposure on brain inflammation and oxidative stress in male mice offspring

YL Chan, S Saad, C Pollock, B Oliver, I Al-Odat… - Scientific reports, 2016 - nature.com
Maternal cigarette smoke exposure (SE) during gestation can cause lifelong adverse effects
in the offspring's brain. Several factors may contribute including inflammation, oxidative …

Inhibitory effects of cigarette smoke extract on neural crest migration occur through suppression of R-spondin1 expression via aryl hydrocarbon receptor

A Sanbe, R Mizutani, N Miyauchi, J Yamauchi… - Naunyn-Schmiedeberg's …, 2009 - Springer
Although it is known that smoking during pregnancy induces fetal malformations, few basic
studies at the molecular level are currently available. Since it is known that neural crest cells …

Perinatal nicotine exposure alters lung development and induces HMGB1‐RAGE expression in neonatal mice

CY Tsai, HC Chou, CM Chen - Birth Defects Research, 2021 - Wiley Online Library
Background Maternal nicotine exposure during gestation and lactation adversely affect lung
development of their children. High‐mobility group box 1 (HMGB1) is the encoded non …