Over 65 million people suffer from recurrent, unprovoked seizures. The lack of validated
biomarkers specific for myriad forms of epilepsy makes diagnosis challenging. Diagnosis …

Epilepsy is part of the clinical phenotype in nearly 40% of children with mitochondrial
disease, yet the underlying molecular mechanisms remain poorly understood. Energy …

Mitochondrial diseases are a group of diseases caused by dysfunctional mitochondria,
organelles that generate energy for the cell. Mitochondrial diseases are often caused by …

Mitochondrial dysfunction has been identified as one potential cause of epileptic seizures.
Impaired mitochondrial function has been reported for the seizure focus of patients with …

Mitochondrial oxidative stress and dysfunction are contributing factors to various
neurological disorders. Recently, there has been increasing evidence supporting the …

Mitochondrial dysfunction has been implicated as a contributing factor in diverse acute and
chronic neurological disorders. However, its role in the epilepsies has only recently …

Epilepsy is the most common neurologic disorder worldwide and is characterized by
recurrent unprovoked seizures. The mitochondrial (mt) respiratory chain is the final common …

Mitochondrial dysfunction and oxidative stress contribute to several neurologic disorders
and have recently been implicated in acquired epilepsies such as temporal lobe epilepsy …

Mitochondrial dysfunction has gained considerable interest as a potential cause of epileptic
seizures and therapy-resistant forms of severe epilepsy. Impairment of mitochondrial …

Epilepsy is a common and heterogeneous neurological disorder arising from biochemical
and molecular events that are incompletely understood. To effectively manage epilepsies, it …