A comprehensive assessment of apigenin as an antiproliferative, proapoptotic, antiangiogenic and immunomodulatory phytocompound
Apigenin (4′, 5, 7-trihydroxyflavone)(Api) is an important component of the human diet,
being distributed in a wide number of fruits, vegetables and herbs with the most important …
being distributed in a wide number of fruits, vegetables and herbs with the most important …
Role of induced programmed cell death in the chemopreventive potential of apigenin
JY Jang, B Sung, ND Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
The flavonoid apigenin (4′, 5, 7-trihydroxyflavone), which is one of the most widely
distributed phytochemicals in the plant kingdom, is one of the most thoroughly investigated …
distributed phytochemicals in the plant kingdom, is one of the most thoroughly investigated …
Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29)
Abstract Apigenin (4′, 5, 7-trihydroxyflavone) is one of the leading components supporting
targeted treatment options. We explored the cytotoxic and apoptotic effects of various doses …
targeted treatment options. We explored the cytotoxic and apoptotic effects of various doses …
Pharmacological properties of 4′, 5, 7-Trihydroxyflavone (apigenin) and its impact on cell signaling pathways
Plant bioactive compounds, particularly apigenin, have therapeutic potential and functional
activities that aid in the prevention of infectious diseases in many mammalian bodies and …
activities that aid in the prevention of infectious diseases in many mammalian bodies and …
Apigenin induces apoptosis in Hep G2 cells: possible role of TNF-α and IFN-γ
TH Khan, S Sultana - Toxicology, 2006 - Elsevier
Flavonoids are one of the biologically active plant food constituents, possessing potential
chemopreventive properties against a wide variety of chronic diseases. Apigenin, a common …
chemopreventive properties against a wide variety of chronic diseases. Apigenin, a common …
Apigenin, a dietary flavonoid, induces apoptosis, DNA damage, and oxidative stress in human breast cancer MCF-7 and MDA MB-231 cells
Apigenin is found in several dietary plant foods such as vegetables and fruits. To investigate
potential anticancer properties of apigenin on human breast cancer, ER-positive MCF-7 and …
potential anticancer properties of apigenin on human breast cancer, ER-positive MCF-7 and …
Plant flavone apigenin: an emerging anticancer agent
E Shankar, A Goel, K Gupta, S Gupta - Current pharmacology reports, 2017 - Springer
Research in cancer chemoprevention provides convincing evidence that increased intake of
vegetables and fruits may reduce the risk of several human malignancies. Phytochemicals …
vegetables and fruits may reduce the risk of several human malignancies. Phytochemicals …
Apigenin: A natural bioactive flavone-type molecule with promising therapeutic function
There exist overwhelming evidence that plant-derived bioactive flavonoids possess strong
therapeutic activities against cancer, cardiovascular diseases, and age-related …
therapeutic activities against cancer, cardiovascular diseases, and age-related …
The potential role of apigenin in cancer prevention and treatment
Cancer is the leading cause of death worldwide. In spite of advances in the treatment of
cancer, currently used treatment modules including chemotherapy, hormone therapy …
cancer, currently used treatment modules including chemotherapy, hormone therapy …
Apigenin as an anticancer agent
Apigenin is an edible plant‐derived flavonoid that has been reported as an anticancer agent
in several experimental and biological studies. It exhibits cell growth arrest and apoptosis in …
in several experimental and biological studies. It exhibits cell growth arrest and apoptosis in …