Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, progressive in nature, and
known to have a negative impact on mortality, morbidity, and quality of life. Patients requiring …

Although rarely life‐threatening on short term, atrial fibrillation leads to increased mortality
and decreased quality of life through its complications, including heart failure and stroke …

Optogenetic methods enable selective de-and hyperpolarization of cardiomyocytes
expressing light-sensitive proteins within the myocardium. By using light, this technology …

Background Optogenetics could offer a solution to the current lack of an ambulatory method
for the rapid automated cardioversion of atrial fibrillation (AF), but key translational aspects …

Cardiac optogenetics is an exciting new methodology in which light-sensitive ion channels
are expressed in heart tissue to enable optical control of bioelectricity. This technology has …

Successful treatment of atrial fibrillation (AF) is difficult to achieve because the arrhythmia
exhibits a high rate of recurrence. Intuitively, restoring sinus rhythm appears the best …

Aims The primary goal in the treatment of symptomatic atrial fibrillation/flutter (AF) is to
restore sinus rhythm by cardioversion. Electrical shocks are highly effective, but have to be …

Aims The most efficient way to acutely restore sinus rhythm from atrial fibrillation (AF) is
electrical cardioversion, which is painful without adequate sedation. Recent studies in …

Optogenetics is an exciting new technology in which viral gene or cell delivery is used to
inscribe light sensitivity in excitable tissue to enable optical control of bioelectric behavior …

Cardiac optogenetics is an emergent research area involving the delivery of light-sensitive
proteins (opsins) to excitable heart tissue to enable optical modulation of cardiac electrical …