Hyaluronic acid (HA) represents a natural polysaccharide which has attracted significant
attention owing to its improved tumor targeting capacity, enzyme degradation capacity, and …

Background Hyaluronic acid (HA) has been widely used as one of major components of
nanocarriers for cancer imaging and therapy. HA possesses hydrophilic and anionic …

Hyaluronic acid (HA) is a natural polysaccharide that has gained much attention due to its
biocompatibility, enzyme degradation capacity and active tumor targeting capacity. Its …

In recent years, biomacromolecules have been widely used in anti-tumor delivery systems
due to the biocompatibility and biodegradability. However, their applications are limited due …

Hyaluronic acid (HA) is a relatively new polymer for the construction of drug delivery
systems. CD44 and the receptor for HA-mediated motility play a key role in vivo for the …

Hyaluronic acid (HA) has been widely investigated in cancer therapy due to its excellent
characteristics. HA, which is a linear anionic polymer, has biocompatibility, biodegradability …

Rapid development of stimuli-responsive drug delivery systems (DDSs) for tumor therapy
has raised increasing interest in recent decades, and many nanomedicines are prepared to …

The overexpression of CD44 in cancer cells reroutes number of oncogenic pathways
including the central Pi3K/Akt/NF-kB pathway leading to cancer progression and …

Introduction: Hyaluronic acid (HA) has emerged as a promising applicant for the tumor-
targeted delivery of various therapeutic agents. Because of its biocompatibility …

Hyaluronic acid (HA), a main component of the extracellular matrix, is widely utilized to
deliver anticancer drugs due to its biocompatibility, biodegradability, non-toxicity, non …