[HTML][HTML] Emerging roles of hydrogen sulfide in inflammatory and neoplastic colonic diseases

FF Guo, TC Yu, J Hong, JY Fang - Frontiers in physiology, 2016 - frontiersin.org
Hydrogen sulfide (H2S) is a toxic gas that has been recognized as an important mediator of
many physiological processes, such as neurodegeneration, regulation of inflammation …

[HTML][HTML] Hydrogen sulfide in physiology and diseases of the digestive tract

SB Singh, HC Lin - Microorganisms, 2015 - mdpi.com
Hydrogen sulfide (H2S) is a Janus-faced molecule. On one hand, several toxic functions
have been attributed to H2S and exposure to high levels of this gas is extremely hazardous …

[HTML][HTML] Implications of hydrogen sulfide in colorectal cancer: Mechanistic insights and diagnostic and therapeutic strategies

H Lin, Y Yu, L Zhu, N Lai, L Zhang, Y Guo, X Lin… - Redox Biology, 2023 - Elsevier
Hydrogen sulfide (H 2 S) is an important signaling molecule in colorectal cancer (CRC). It is
produced in the colon by the catalytic synthesis of the colonocytes' enzymatic systems and …

Production of hydrogen sulfide by the intestinal microbiota and epithelial cells and consequences for the colonic and rectal mucosa

F Blachier, M Andriamihaja… - American Journal …, 2021 - journals.physiology.org
Among bacterial metabolites, hydrogen sulfide (H2S) has received increasing attention. The
epithelial cells of the large intestine are exposed to two sources of H2S. The main one is the …

Hydrogen sulfide: an endogenous mediator of resolution of inflammation and injury

JL Wallace, JGP Ferraz, MN Muscara - Antioxidants & redox …, 2012 - liebertpub.com
Significance: Hydrogen sulfide is emerging as an important mediator of many aspects of
inflammation, and perhaps most importantly as a factor promoting the resolution of …

[HTML][HTML] Role of hydrogen sulfide in inflammatory bowel disease

N Stummer, RG Feichtinger, D Weghuber, B Kofler… - Antioxidants, 2023 - mdpi.com
Hydrogen sulfide (H2S), originally known as toxic gas, has now attracted attention as one of
the gasotransmitters involved in many reactions in the human body. H2S has been assumed …

Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice

I Hirata, Y Naito, T Takagi, K Mizushima… - Digestive diseases and …, 2011 - Springer
Background Endogenous hydrogen sulfide (H 2 S) is increasingly being recognized as an
important gaseous physiological mediator. Accumulating evidence shows the functions of H …

Hydrogen sulfide-based therapeutics and gastrointestinal diseases: translating physiology to treatments

MV Chan, JL Wallace - American Journal of Physiology …, 2013 - journals.physiology.org
Hydrogen sulfide (H2S) is a gaseous meditator that has various physiological and
pathophysiological roles in the body. It has been shown to be an important mediator of …

[HTML][HTML] Hydrogen sulfide lowers proliferation and induces protective autophagy in colon epithelial cells

YC Wu, XJ Wang, L Yu, FKL Chan, ASL Cheng, J Yu… - PloS one, 2012 - journals.plos.org
Hydrogen sulfide (H2S) is a gaseous bacterial metabolite that reaches high levels in the
large intestine. In the present study, the effect of H2S on the proliferation of normal and …

Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21

WJ Cai, MJ Wang, LH Ju, C Wang… - Cell biology …, 2010 - Wiley Online Library
H2S (hydrogen sulfide), regarded as the third gaseous transmitter, is implicated in ulcerative
colitis and colorectal cancers. The present study investigates the effects of H2S on cell …