Effects of Zinc Supplementation in the Elderly with Focus on Muscle Mass, Dry Skin, and Gut Microbiota

N Nakagawa, T Enokiya, S Tochitani, M Nakahigashi… - BPB Reports, 2023 - jstage.jst.go.jp
Background and aim: Zinc is one of the most important essential trace elements found in
more than 300 enzymes in humans, and the risk of zinc deficiency has been shown to …

Serum levels of the Micronutrient Zinc Decrease with Advancing Age in Normally Nourished Older Adults Over 75 Years of Age

M Takahashi, T Suzuki, A Takagi… - … of Nutrition & …, 2016 - mathewsopenaccess.com
Adequate daily nutrient intake is one of the most important factors contributing to the
achievement of healthy aging. In this study, we investigated changes in blood nutrients over …

[HTML][HTML] Effect of zinc supplementation on serum zinc concentration and T cell proliferation in nursing home elderly: a randomized, double-blind, placebo-controlled …

JB Barnett, MC Dao, DH Hamer, R Kandel… - The american journal of …, 2016 - Elsevier
Background: Zinc is essential for the regulation of immune response. T cell function declines
with age. Zinc supplementation has the potential to improve the serum zinc concentrations …

[HTML][HTML] Zinc is an antioxidant and anti-inflammatory agent: its role in human health

AS Prasad - Frontiers in nutrition, 2014 - frontiersin.org
Zinc supplementation trials in the elderly showed that the incidence of infections was
decreased by approximately 66% in the zinc group. Zinc supplementation also decreased …

Main biomarkers associated with age-related plasma zinc decrease and copper/zinc ratio in healthy elderly from ZincAge study

R Giacconi, L Costarelli, F Piacenza, A Basso… - European journal of …, 2017 - Springer
Abstract Purpose Zinc (Zn) plays an essential role in many biological processes including
immune response. Impaired Zn status promotes immune dysfunction, and it has been …

Plasma zinc in institutionalized elderly individuals: Relation with immune and cardiometabolic biomarkers

MC Sales, LP de Oliveira, NL de Araújo Cabral… - Journal of Trace …, 2018 - Elsevier
Abstract Changes in zinc metabolism caused by aging and the institutionalization process
may contribute to zinc deficiency in elderly individuals. Hypozincemia results in changes in …

Association between dietary zinc intake, serum zinc level and multiple comorbidities in older adults

S Ruangritchankul, C Sumananusorn, J Sirivarasai… - Nutrients, 2023 - mdpi.com
Zinc is one of the essential micronutrients in the geriatric population, but the importance of
zinc status and dietary zinc intake has been poorly characterized. We aimed to explore the …

[HTML][HTML] Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress

AS Prasad, FWJ Beck, B Bao, JT Fitzgerald… - The American journal of …, 2007 - Elsevier
Background: Zinc deficiency, cell-mediated immune dysfunction, susceptibility to infections,
and increased oxidative stress have been observed in elderly subjects (ie, those> 55 y old) …

Zinc supplementation for the treatment or prevention of disease: current status and future perspectives

H Haase, S Overbeck, L Rink - Experimental gerontology, 2008 - Elsevier
Zinc is a nutritionally essential trace element, and thus zinc deficiency may severely affect
human health. Many studies were published in which the effect of nutritional zinc …

Zinc and the immune system of elderly

KH Ibs, P Gabriel, L Rink - Advances in Cell Aging and Gerontology, 2002 - Elsevier
Conclusions Various groups of people are predisposed to zinc deficiency, particularly the
aged population. Even in the very healthy elderly, zinc levels are decreased compared with …