Mammalian organogenesis involves a sequential program to generate cells with specific
fates and phenotypes from a common primordium, which is hypothesized to be the …

Development of the anterior pituitary gland ultimately leads to the appearance of five distinct
cell types that are defined by the trophic hormones which they produce, providing an …

▪ Abstract During the development of the pituitary gland, distinct hormone-producing cell
types arise from a common population of ectodermal progenitors, providing an instructive …

The pituitary gland is a central endocrine organ regulating basic physiological functions,
including growth, the stress response, reproduction, metabolic homeostasis, and lactation …

The mammalian anterior pituitary gland is a compound endocrine organ that regulates
reproductive development and fitness, growth, metabolic homeostasis, the response to …

Significant advances have been made in defining the transcription cascade that is
responsible for the early steps of pituitary formation and the environmental signals that …

Many common morphogenic, signaling and transcriptional hierarchy themes exist with
respect to a number of different model systems representing mammalian organogenesis …

Emergence of distinct cell types from a common primordium during pituitary development
occurs in response to opposing signaling gradients that induce an overlapping temporal and …

The development of the pituitary gland has provided an instructive model system for
exploring the mechanisms by which differentiated cell types arise from a common …

The development of the anterior pituitary gland occurs in distinct sequential developmental
steps, leading to the formation of a complex organ containing five different cell types …