Radiation therapy (RT) has emerged as one of the most promising anti-tumor strategies for
neuroblastoma. Nevertheless, the special tumor microenvironment (TME), including hypoxic …

The prosperity of chemodynamic therapy provides a new strategy for tumor treatment.
However, the lack of reactive oxygen species and the specific reductive tumor …

Chemodynamic therapy (CDT) has attracted increasing attention in tumor treatment but is
limited by insufficient endogenous H2O2. Moreover, it is challenging for monotherapy to …

Chemodynamic therapy (CDT) eradicates tumors by intratumoral catalytic chemical reaction
and subsequently disrupts redox homeostasis, which shows tumor specific reactive oxygen …

Developing safe, effective and targeting radiosensitizers with clear action mechanisms to
achieve synergistic localized cancer treatment is an important strategy for radiotherapy …

Background Though the combination of photodynamic therapy (PDT) and chemodynamic
therapy (CDT) appears to be very attractive in cancer treatment, hypoxia and overproduced …

The treatment of bone metastases remains an enormous challenge in clinical application.
Strategies utilizing reactive oxygen species (ROS) to induce cell death show great potential …

How to boost the therapeutic efficiency is still the key to translation of anticancer
nanomedicine from preclinical investigations to clinical practice. In this work, we proposed to …

The efficacy of free radical-based therapeutic strategies is severely hindered by nonspecific
accumulation, premature release and glutathione (GSH) scavenging effects. Herein, a tumor …

Accurate drug delivery is a common topic, and it has always been an aim that scientists
strive to achieve. To address this need, multifunctional and stimulus-sensitive nanoplatforms …