Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations
Pancreatic cancer has the lowest survival rate among human cancers, and there are no
effective markers for its screening and early diagnosis. To identify genetic susceptibility …
effective markers for its screening and early diagnosis. To identify genetic susceptibility …
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22. 1, 1q32. 1 and 5p15. 33
GM Petersen, L Amundadottir, CS Fuchs, P Kraft… - Nature …, 2010 - nature.com
We conducted a genome-wide association study of pancreatic cancer in 3,851 affected
individuals (cases) and 3,934 unaffected controls drawn from 12 prospective cohort studies …
individuals (cases) and 3,934 unaffected controls drawn from 12 prospective cohort studies …
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer
BM Wolpin, C Rizzato, P Kraft, C Kooperberg… - Nature …, 2014 - nature.com
We performed a multistage genome-wide association study including 7,683 individuals with
pancreatic cancer and 14,397 controls of European descent. Four new loci reached genome …
pancreatic cancer and 14,397 controls of European descent. Four new loci reached genome …
[HTML][HTML] Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32. 1, 5p15. 33 and 8q24. 21
Genome-wide association studies (GWAS) have identified common pancreatic cancer
susceptibility variants at 13 chromosomal loci in individuals of European descent. To identify …
susceptibility variants at 13 chromosomal loci in individuals of European descent. To identify …
[HTML][HTML] Genome-wide association study of pancreatic cancer in Japanese population
SK Low, A Kuchiba, H Zembutsu, A Saito, A Takahashi… - PloS one, 2010 - journals.plos.org
Pancreatic cancer shows very poor prognosis and is the fifth leading cause of cancer death
in Japan. Previous studies indicated some genetic factors contributing to the development …
in Japan. Previous studies indicated some genetic factors contributing to the development …
[HTML][HTML] Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer
Abstract In 2020, 146,063 deaths due to pancreatic cancer are estimated to occur in Europe
and the United States combined. To identify common susceptibility alleles, we performed the …
and the United States combined. To identify common susceptibility alleles, we performed the …
A transcriptome-wide association study identifies novel candidate susceptibility genes for pancreatic cancer
Background Although 20 pancreatic cancer susceptibility loci have been identified through
genome-wide association studies in individuals of European ancestry, much of its heritability …
genome-wide association studies in individuals of European ancestry, much of its heritability …
Common variation at 2p13. 3, 3q29, 7p13 and 17q25. 1 associated with susceptibility to pancreatic cancer
EJ Childs, E Mocci, D Campa, PM Bracci, S Gallinger… - Nature …, 2015 - nature.com
Pancreatic cancer is the fourth leading cause of cancer death in the developed world. Both
inherited high-penetrance mutations in BRCA2 (ref.), ATM, PALB2 (ref.), BRCA1 (ref.) …
inherited high-penetrance mutations in BRCA2 (ref.), ATM, PALB2 (ref.), BRCA1 (ref.) …
[HTML][HTML] Pancreatic cancer susceptibility loci and their role in survival
C Rizzato, D Campa, N Giese, J Werner… - PloS one, 2011 - journals.plos.org
Pancreatic cancer has one of the worst mortality rates of all cancers. Little is known about its
etiology, particularly regarding inherited risk. The PanScan project, a genome-wide …
etiology, particularly regarding inherited risk. The PanScan project, a genome-wide …
A transcriptome-wide association study identifies candidate susceptibility genes for pancreatic cancer risk
Pancreatic cancer is among the most well-characterized cancer types, yet a large proportion
of the heritability of pancreatic cancer risk remains unclear. Here, we performed a large …
of the heritability of pancreatic cancer risk remains unclear. Here, we performed a large …