Despite considerable success in treatment of early stage localized prostate cancer (PC),
acute inadequacy of late stage PC treatment and its inherent heterogeneity poses a …

Advances in science and technology have allowed us to manipulate the mouse genome and
analyse the effect of specific genetic alterations on the development of prostate cancer in …

Despite major improvement in treatment of early stage localised prostate cancer, the
distinction between indolent tumors and those that will become aggressive, as well as the …

There has been substantial progress made recently in the effort to model human prostate
cancer in mice. Several mutant mice have been generated which mimic various aspects of …

Prostate cancer continues to be the second leading cancer related death among men. In
order to more fully develop effective prevention and intervention strategies for this prevalent …

Simple Summary This review explores in vivo models of prostate cancer currently published
in the literature, with the focus on the prostate cancer mouse models that have recently been …

The incidence and mortality from prostate cancer (PCa) are on the rise which poses a major
public health concern worldwide. In this narrative review, we have summarized the …

This review is focused on mouse models for prostate cancer that have been designed on the
basis of genetic alterations that are frequently found in human prostate cancer. It begins with …

The pathogenetic basis of prostate cancer remains highly elusive; its clarification could be
facilitated greatly by laboratory and clinical models of the disease. Although the genetically …

In recent years, numerous mouse models have been generated that recapitulate salient
features of prostate carcinogenesis in humans. Here we review progress in the generation …