The systematic codon usage bias has an important effect on genetic adaption in native species
AS Panja - Gene, 2024 - Elsevier
Random mutations increase genetic variety and natural selection enhances adaption over
generations. Codon usage biases (CUB) provide clues about the genome adaptation …
generations. Codon usage biases (CUB) provide clues about the genome adaptation …
The application of population genetics in the study of codon usage bias
K Zeng - Codon 825 evolution: mechanisms and models, 2012 - books.google.com
A widely used method for studying the evolutionary forces acting on a species is to
sequence homologous genomic regions from a set of randomly chosen individuals. The …
sequence homologous genomic regions from a set of randomly chosen individuals. The …
Studies on the origin and evolution of codon bias
JC Biro - arXiv preprint arXiv:0807.3901, 2008 - arxiv.org
Background: There is a 3-fold redundancy in the Genetic Code; most amino acids are
encoded by more than one codon. These synonymous codons are not used equally; there is …
encoded by more than one codon. These synonymous codons are not used equally; there is …
[HTML][HTML] A new codon adaptation metric predicts vertebrate body size and tendency to protein disorder
The nearly neutral theory of molecular evolution posits variation among species in the
effectiveness of selection. In an idealized model, the census population size determines …
effectiveness of selection. In an idealized model, the census population size determines …
[HTML][HTML] Does codon bias have an evolutionary origin?
JC Biro - Theoretical Biology and Medical Modelling, 2008 - Springer
Background There is a 3-fold redundancy in the Genetic Code; most amino acids are
encoded by more than one codon. These synonymous codons are not used equally; there is …
encoded by more than one codon. These synonymous codons are not used equally; there is …
Effective population size does not predict codon usage bias in mammals
MD Kessler, MD Dean - Ecology and evolution, 2014 - Wiley Online Library
Synonymous codons are not used at equal frequency throughout the genome, a
phenomenon termed codon usage bias (CUB). It is often assumed that interspecific variation …
phenomenon termed codon usage bias (CUB). It is often assumed that interspecific variation …
Selection on codon bias
R Hershberg, DA Petrov - Annual review of genetics, 2008 - annualreviews.org
In a wide variety of organisms, synonymous codons are used with different frequencies, a
phenomenon known as codon bias. Population genetic studies have shown that …
phenomenon known as codon bias. Population genetic studies have shown that …
[HTML][HTML] Intragenomic variation in non-adaptive nucleotide biases causes underestimation of selection on synonymous codon usage
Patterns of non-uniform usage of synonymous codons vary across genes in an organism
and between species across all domains of life. This codon usage bias (CUB) is due to a …
and between species across all domains of life. This codon usage bias (CUB) is due to a …
[PDF][PDF] Codon usage bias is evolutionarily conserved
BMH Keng, OYW Chan, MHT Ling - Asia Pacific Journal of Life Sciences, 2014 - Citeseer
Codon usage bias (CUB) reflects the frequency distribution of codons usage in the genome.
Several studies suggest that CUB is based on the combinations, which are most chemically …
Several studies suggest that CUB is based on the combinations, which are most chemically …
Codon models as a vehicle for reconciling population genetics with inter-specific sequence data
Much of modern biological research aims to characterize the relationship between genotype
and phenotype. Evolutionary biology is more ambitious. An understanding of how genotype …
and phenotype. Evolutionary biology is more ambitious. An understanding of how genotype …