Preterm labor: one syndrome, many causes

R Romero, SK Dey, SJ Fisher - Science, 2014 - science.org
Preterm birth is associated with 5 to 18% of pregnancies and is a leading cause of infant
morbidity and mortality. Spontaneous preterm labor, a syndrome caused by multiple …

A systematic approach to the management of preterm labor

ER Norwitz, JN Robinson - Seminars in perinatology, 2001 - Elsevier
Preterm birth occurs in 7% to 12% of all deliveries, but accounts for over 85% of all perinatal
morbidity and mortality. Although the ability of obstetric care providers to identify women at …

The biological basis and prevention of preterm birth

GC Di Renzo, V Tosto, I Giardina - Best Practice & Research Clinical …, 2018 - Elsevier
The time of birth is a critical determinant of perinatal and long-term outcomes. Preterm birth
is still the first cause of infant mortality and morbidity; unfortunately, rates of preterm birth …

Parturition

R Smith - New England Journal of Medicine, 2007 - Mass Medical Soc
Preterm birth is associated with high rates of infant mortality and morbidity. This review
emphasizes that the onset of labor entails a molecular collaboration between the mother …

Prevention of preterm birth: harnessing science to address the global epidemic

CE Rubens, Y Sadovsky, L Muglia… - Science translational …, 2014 - science.org
Preterm birth is a leading cause of infant morbidity and mortality worldwide, but current
interventions to prevent prematurity are largely ineffective. Preterm birth is increasingly …

Prevention of preterm delivery

HN Simhan, SN Caritis - New England Journal of Medicine, 2007 - Mass Medical Soc
Although preterm birth (at< 37 weeks' gestation) is sometimes indicated for the health of the
mother or her fetus, spontaneous preterm births occur as a consequence of spontaneous …

The molecular mechanisms of term and preterm labor: recent progress and clinical implications

JA Keelan, M Coleman, MD Mitchell - Clinical obstetrics and …, 1997 - journals.lww.com
Human parturition is characterized by a complex interplay of autocrine/paracrine factors and
signaling molecules within intrauterine tissues. The prevailing view is that factors produced …

[PDF][PDF] The preterm labor syndrome

R Romero, M Mazor, H Munoz, R Gomez… - Annals of the New …, 1994 - academia.edu
Prematurity is the leading cause of perinatal morbidity and mortality worldwide.'It affects 5-
10% of births. Preterm neonates have a 120 times higher risk of death than term neonate …

Preterm birth: causes, consequences, and prevention

RE Behrman, AS Butler - 2007 - pubmed.ncbi.nlm.nih.gov
In 2004, 12.5 percent of births in the United States were preterm; that is, born at less than 37
completed weeks of gestation. This rate has increased steadily in the past decade. There …

[HTML][HTML] The preterm parturition syndrome and its implications for understanding the biology, risk assessment, diagnosis, treatment and prevention of preterm birth

F Gotsch, F Gotsch, R Romero, O Erez… - The Journal of …, 2009 - Taylor & Francis
The syndromic nature of spontaneous labour was a concept first proposed in 1994 [1]. It has
important implications for understanding the biology of preterm parturition, and also, setting …