Advancements in the analytical quantification of nitroxidative stress biomarker 3-nitrotyrosine in biological matrices
M Bandookwala, D Thakkar… - Critical Reviews in …, 2020 - Taylor & Francis
Dysfunction of the antioxidant system or mutations in the gene may result in the elevated
production of certain biomarkers. 3-nitrotyrosine (3-NT) is one such promising biomarker of …
production of certain biomarkers. 3-nitrotyrosine (3-NT) is one such promising biomarker of …
3-Nitrotyrosine quantification methods: Current concepts and future challenges
Abstract Background Measurement of 3-nitrotyrosine (3-NT) in biological samples can be
used as a biomarker of nitrosative stress, since it is very stable and suitable for analysis …
used as a biomarker of nitrosative stress, since it is very stable and suitable for analysis …
A novel mixed-mode solid phase extraction coupled with LC–MS/MS for the re-evaluation of free 3-nitrotyrosine in human plasma as an oxidative stress biomarker
XS Li, S Li, G Kellermann - Talanta, 2015 - Elsevier
Nitrotyrosine (3-NT) has been widely adopted as a biomarker of oxidative stress. However,
an enormous range of reported concentrations of 3-NT in biological matrices indicated an …
an enormous range of reported concentrations of 3-NT in biological matrices indicated an …
Fluorogenic tagging of peptide and protein 3-nitrotyrosine with 4-(aminomethyl) benzenesulfonic acid for quantitative analysis of protein tyrosine nitration
VS Sharov, ES Dremina, NA Galeva, GS Gerstenecker… - Chromatographia, 2010 - Springer
Abstract Protein 3-nitrotyrosine (3-NT) has been recognized as an important biomarker of
nitroxidative stress associated with inflammatory and degenerative diseases, and biological …
nitroxidative stress associated with inflammatory and degenerative diseases, and biological …
What we—authors, reviewers and editors of scientific work—can learn from the analytical history of biological 3-nitrotyrosine
D Tsikas - Journal of Chromatography B, 2017 - Elsevier
Tyrosine and tyrosine residues in proteins are attacked by the reactive oxygen and nitrogen
species peroxynitrite (O= N–OO–) to generate 3-nitrotyrosine (3-NT) and 3-nitrotyrosine …
species peroxynitrite (O= N–OO–) to generate 3-nitrotyrosine (3-NT) and 3-nitrotyrosine …
Analytical methods for 3-nitrotyrosine quantification in biological samples: the unique role of tandem mass spectrometry
D Tsikas - Amino acids, 2012 - Springer
Reactive-nitrogen species, such as peroxynitrite (ONOO−) and nitryl chloride (NO 2 Cl),
react with the aromatic ring of tyrosine in soluble amino acids and in proteins to form 3 …
react with the aromatic ring of tyrosine in soluble amino acids and in proteins to form 3 …
Recent methodological advances in the mass spectrometric analysis of free and protein-associated 3-nitrotyrosine in human plasma
D Tsikas, K Caidahl - Journal of Chromatography B, 2005 - Elsevier
l-Tyrosine and l-tyrosine residues in proteins are attacked by various reactive-nitrogen
species (RNS) including peroxynitrite to form 3-nitrotyrosine (NO2Tyr) and protein …
species (RNS) including peroxynitrite to form 3-nitrotyrosine (NO2Tyr) and protein …
Development of a new HPLC-based method for 3-nitrotyrosine quantification in different biological matrices
D Teixeira, C Prudêncio, M Vieira - Journal of Chromatography B, 2017 - Elsevier
Background The nitration of tyrosine residues in proteins is associated with nitrosative
stress, resulting in the formation of 3-nitrotyrosine (3-NT). 1 3-NT levels in biological samples …
stress, resulting in the formation of 3-nitrotyrosine (3-NT). 1 3-NT levels in biological samples …
A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells
AR Knight, EL Taylor, R Lukaszewski… - Free Radical Biology …, 2018 - Elsevier
The generation of 3-nitrotyrosine, within proteins, is a post-translational modification
resulting from oxidative or nitrative stress. It has been suggested that this modification could …
resulting from oxidative or nitrative stress. It has been suggested that this modification could …
Rapid and sensitive determination of protein-nitrotyrosine by ELISA: Application to human plasma
D Weber, N Kneschke, S Grimm, I Bergheim… - Free Radical …, 2012 - Taylor & Francis
3-Nitrotyrosine (3NT) is known as an important indicator of nitrosative stress and has been
linked to various diseases. Our aim was to develop an indirect ELISA (enzyme-linked …
linked to various diseases. Our aim was to develop an indirect ELISA (enzyme-linked …