Ryanodine receptors (RyRs) and inositol 1, 4, 5‐trisphosphate receptors (IP3Rs) are
calcium (Ca2+) release channels on the endo/sarcoplasmic reticulum (ER/SR). Here we …

Intracellular Ca2+ release through ryanodine receptor (RyR) and inositol trisphosphate
receptor (IP3R) channels is supported by a complex network of additional proteins that are …

Calcium (Ca2+) release from intracellular stores controls numerous cellular processes,
including cardiac and skeletal muscle contraction, synaptic transmission and metabolism …

The two major calcium (Ca 2+) release channels on the sarco/endoplasmic reticulum
(SR/ER) are inositol 1, 4, 5-trisphosphate and ryanodine receptors (IP 3 Rs and RyRs). They …

Calcium (Ca2+) ions are second messengers in signaling pathways in all types of cells.
They regulate muscle contraction, electrical signals which determine the cardiac rhythm and …

The endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) form major intracellular
Ca 2+ stores. Ryanodine receptors (RyRs) are large tetrameric ion channels in the SR and …

Calcium (Ca2) ions are second messengers in numerous sig-naling pathways in all cell
types. 1 In the heart, Ca2 regulates muscle contraction, electrical signals that determine the …

Inositol 1, 4, 5-trisphosphate receptors (IP 3 R) and ryanodine receptors (RyR) mediate the
release of endoplasmic and sarcoplasmic reticulum (ER/SR) Ca 2+ stores and regulate Ca …

Ca2+-release channels are giant membrane proteins that control the release of Ca2+ from
the endoplasmic and sarcoplasmic reticulum. The two members, ryanodine receptors …

Intracellular Ca2+-release channels on the sarcoplasmic reticulum of striated muscle
[ryanodine receptors (RyRs)] and on the endoplasmic reticulum of almost all types of cells …