Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes

K McDowell, C Adamson, C Jackson… - European Journal of …, 2024 - Wiley Online Library
Abstract Aims Neuropeptide Y (NPY) is the most abundant neuropeptide found in the heart
and is released alongside norepinephrine following prolonged sympathetic activation, a …

Evaluation of plasma neuropeptide Y levels in patients with congestive heart failure

JJ Liu, SG Shi, QD Han - Zhonghua nei ke za zhi, 1994 - europepmc.org
Plasma neuropeptide Y (NPY) was measured by radioimmunoassay in 43 patients with
congestive heart failure (CHF) and 20 healthy control subjects. The results showed that …

Neuropeptide Y predicts cardiovascular events in chronic kidney disease patients: a cohort study

C Zoccali, G D'Arrigo, D Leonardis, P Pizzini… - Journal of …, 2019 - journals.lww.com
Background: Neuropeptide Y (NPY) is a multifaceted sympathetic neurotransmitter
regulating reflex cardiovascular control, myocardial cell growth, inflammation and innate …

Neuropeptide Y, left ventricular mass and function in patients with end stage renal disease

C Zoccali, F Mallamaci, G Tripepi… - Journal of …, 2003 - journals.lww.com
Objective Neuropeptide Y (NPY) is released during sympathetic stimulation and mediates
the central effects of the adipostatic hormone leptin. The plasma concentration of NPY and …

Coronary sinus neuropeptide Y levels and adverse outcomes in patients with stable chronic heart failure

OA Ajijola, NA Chatterjee, MJ Gonzales… - JAMA …, 2020 - jamanetwork.com
Importance Chronic heart failure (CHF) is associated with increased sympathetic drive and
may increase expression of the cotransmitter neuropeptide Y (NPY) within sympathetic …

Venous neuropeptide Y receptor responsiveness in patients with chronic heart failure

Q Feng, ML Lambert, ID Callow… - Clinical Pharmacology …, 2000 - Wiley Online Library
Background Chronic heart failure is associated with increased sympathetic nerve activity
and elevated plasma neuropeptide Y levels. The aim of this study was to investigate whether …

Prospective study of neuropeptide y as an adverse cardiovascular risk factor in end-stage renal disease

C Zoccali, F Mallamaci, G Tripepi… - Journal of the …, 2003 - journals.lww.com
Chronic renal insufficiency is a situation characterized by high plasma concentration of
neuropeptide Y (NPY). Because this neuropeptide interferes with cardiovascular (CV) …

Plasma neuropeptide Y on admission to a coronary care unit: raised levels in patients with left heart failure

J Hulting, A Sollevi, B Ullman… - Cardiovascular …, 1990 - academic.oup.com
Study objective–The aim of the study was to measure plasma neuropeptide Y, which is
related to sympathetic nerve stimulation, in patients admitted to a coronary care unit and to …

Neuropeptide Y: A Carondiac Sympathetic Cotransmitter?

M Haass - Advances in Pharmacology, 1997 - Elsevier
Publisher Summary This chapter focuses on the attempts to further characterize the
relationship of NPY to NE release under physiological and pathophysiological conditions …

Elevation of plasma neuropeptide Y levels in congestive heart failure

AS Maisel, NA Scott, HJ Motulsky, MC Michel… - The American journal of …, 1989 - Elsevier
Abstract purpose: Our objectives were to assess whether plasma neuropeptide Y (NPY)
levels are elevated in patients with congestive heart failure (CHF) and whether or not NPY …