Purinergic signalling in neuron–glia interactions
RD Fields, G Burnstock - Nature Reviews Neuroscience, 2006 - nature.com
Activity-dependent release of ATP from synapses, axons and glia activates purinergic
membrane receptors that modulate intracellular calcium and cyclic AMP. This enables glia to …
membrane receptors that modulate intracellular calcium and cyclic AMP. This enables glia to …
ATP: a ubiquitous gliotransmitter integrating neuron–glial networks
AM Butt - Seminars in cell & developmental biology, 2011 - Elsevier
Astrocytes are ideally situated to integrate glial and neuronal functions and neurovascular
coupling by way of their multiple contacts with neurons, glia and blood vessels. There is a …
coupling by way of their multiple contacts with neurons, glia and blood vessels. There is a …
Pathophysiology of astroglial purinergic signalling
H Franke, A Verkhratsky, G Burnstock, P Illes - Purinergic signalling, 2012 - Springer
Astrocytes are fundamental for central nervous system (CNS) physiology and are the fulcrum
of neurological diseases. Astroglial cells control development of the nervous system …
of neurological diseases. Astroglial cells control development of the nervous system …
Purinergic transmission in the central nervous system
RA North, A Verkhratsky - Pflügers Archiv, 2006 - Springer
Abstract The adenosine 5′-triphosphate (ATP), discovered in 1929 by Karl Lohman, Cyrus
Hartwell Fiske, and Yellagaprada SubbaRow, acts as an important extracellular signaling …
Hartwell Fiske, and Yellagaprada SubbaRow, acts as an important extracellular signaling …
A central role for ATP signalling in glial interactions in the CNS
A Rivera, I Vanzulli, AM Butt - Current drug targets, 2016 - ingentaconnect.com
The purine ATP has a prominent regulatory role in CNS function and pathology due to its
actions on glial cells-microglia, astrocytes and oligodendrocytes. ATP serves as an …
actions on glial cells-microglia, astrocytes and oligodendrocytes. ATP serves as an …
ATP-mediated signalling in the central synapses
U Lalo, Y Pankratov - Neuropharmacology, 2023 - Elsevier
ATP released from the synaptic terminals and astrocytes can activate neuronal P2 receptors
at a variety of locations across the CNS. Although the postsynaptic ATP-mediated signalling …
at a variety of locations across the CNS. Although the postsynaptic ATP-mediated signalling …
Introduction to purinergic signalling in the brain
G Burnstock - Glioma signaling, 2020 - Springer
ATP is a cotransmitter with glutamate, noradrenaline, GABA, acetylcholine and dopamine in
the brain. There is a widespread presence of both adenosine (P1) and P2 nucleotide …
the brain. There is a widespread presence of both adenosine (P1) and P2 nucleotide …
[HTML][HTML] ATP released by astrocytes mediates glutamatergic activity-dependent heterosynaptic suppression
Extracellular ATP released from axons is known to assist activity-dependent signaling
between neurons and Schwann cells in the peripheral nervous system. Here we report that …
between neurons and Schwann cells in the peripheral nervous system. Here we report that …
P2 receptors and neuronal injury
H Franke, U Krügel, P Illes - Pflügers Archiv, 2006 - Springer
Abstract Extracellular adenosine 5′-triphosphate (ATP) was proposed to be an activity-
dependent signaling molecule that regulates glia–glia and glia–neuron communications …
dependent signaling molecule that regulates glia–glia and glia–neuron communications …
Purinergic signaling orchestrating neuron-glia communication
P Agostinho, D Madeira, L Dias, AP Simões… - Pharmacological …, 2020 - Elsevier
This review discusses the evidence supporting a role for ATP signaling (operated by P 2 X
and P 2 Y receptors) and adenosine signaling (mainly operated by A 1 and A 2A receptors) …
and P 2 Y receptors) and adenosine signaling (mainly operated by A 1 and A 2A receptors) …