This study examined sex differences in the regulation of pro-and anti-apoptotic proteins in
cardiac hypertrophy and heart failure due to volume overload induced by arteriovenous (AV) …

Heart failure is known to be associated with an increase in cardiomyocyte apoptosis;
however, neither its occurrence nor the mechanisms involved in hearts failing due to volume …

The exact mechanisms responsible for the progression of heart failure remain unclear. We
investigated the in vivo relationship between the incidence of apoptotic cell death and left …

BACKGROUND: Cardiomyocyte apoptosis is implicated in the pathogenesis of heart failure
and mitochondria play an important role in this mode of cell death. In this study, activity of the …

BACKGROUND: This study examined the sex differences for hemodynamic and
echocardiographic changes in hypertrophied and failing hearts induced by arteriovenous …

Various alterations in molecular and cellular events have been considered as possibly
contributing to the cardiac remodelling that occurs during the transition from compensated …

Background—Left ventricular hypertrophy (LVH) represents both an adaptive response to
increased cardiac work load and a precursor state of heart failure. Recent evidence linked …

In humans, volume overload (VOL) increases the risk of sudden cardiac death, but there is
also important inter-individual variability, presumably because of differences in genetic …

The aim of this study was to test the hypothesis that persistent myocardial apoptosis
contributes to progression of heart failure in a canine model of pacing-induced …

Serum starvation has recently been shown to cause cell death of cardiac fibroblasts and
increased synthesis of extracellular matrix proteins in the surviving cells. In the present …