LncRNA MEG3 regulates ASK1/JNK axis-mediated apoptosis and autophagy via sponging miR-23a in granulosa cells of yak tertiary follicles

X Han, Y Pan, J Fan, M Wang, L Wang, J Wang… - Cellular …, 2023 - Elsevier
Apoptosis and autophagy in granulosa cells (GCs) are highly related to follicular
development and atresia. It has also been reported that they are related to LncRNA MEG3 …

Effect of follicle-stimulating hormone and luteinizing hormone on apoptosis, autophagy, and the release and reception of some steroid hormones in yak granulosa …

H Xiao-Hong, W Meng, P Yang-Yang, F Jiang-Feng… - Cellular …, 2024 - Elsevier
Abstract Follicle-stimulating hormone (FSH), luteinizing hormone (LH), miR-23a, apoptosis
signal-regulating kinase 1 (ASK1)/c-Jun N-terminal kinase (JNK), autophagy and apoptosis …

MiR-23a promotes autophagy of yak cumulus cells to alleviate apoptosis via the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway

X Han, S Yu, Y Cui, J Li, J Fan, L Wang, M Wang… - Theriogenology, 2023 - Elsevier
The ultimate fate of Graafian follicles is ovulation or atresia which relies on the highly
coordinated processes of apoptosis and autophagy in ovarian cells. Long non-coding RNA …

Let-7g induces granulosa cell apoptosis by targeting MAP3K1 in the porcine ovary

R Cao, W Wu, X Zhou, K Liu, B Li, X Huang… - … International Journal of …, 2015 - Elsevier
Follicular atresia mainly results from apoptosis of granulosa cells (GCs). Our previous
microRNA array data indicated that the miRNA let-7g level increases significantly during …

Gga-miR-146b-3p promotes apoptosis and attenuate autophagy by targeting AKT1 in chicken granulosa cells

Q Wei, H Xue, C Sun, J Li, H He, FK Amevor, B Tan… - Theriogenology, 2022 - Elsevier
The normal development of follicles determines the reproductive performance of females.
Granulosa cells (GC) play crucial roles in follicular maturation. Numerous studies have …

miR-21-3p inhibits autophagy of bovine granulosa cells by targeting VEGFA via PI3K/AKT signaling

L Ma, Y Zheng, X Tang, H Gao, N Liu, Y Gao… - …, 2019 - rep.bioscientifica.com
It is well documented that granulosa cell apoptosis is the main reason for follicular atresia
and death; however, increasing evidence suggests that autophagy plays an important role in …

miR-450-5p and miR-202-5p synergistically regulate follicle development in black goat

G Feng, J Liu, Z Lu, Y Li, M Deng, G Liu, B Sun… - International Journal of …, 2022 - mdpi.com
Follicle maturation is a complex biological process governed by numerous factors, and
researchers have observed follicle development by studying the proliferation and apoptosis …

MIR143 inhibits steroidogenesis and induces apoptosis repressed by H3K27me3 in granulosa cells

Y Zhong, L Li, Z Chen, S Diao, Y He… - Frontiers in Cell and …, 2020 - frontiersin.org
The granulosa cell growth factor and apoptotic factor are two factors to determine follicular
apoptosis. Whether ssc-miR-143-3p (MIR143) plays as an apoptosis factor in porcine …

miR-423 sponged by lncRNA NORHA inhibits granulosa cell apoptosis

Y Li, Z Zhang, S Wang, X Du, Q Li - Journal of Animal Science and …, 2023 - Springer
Background Atresia and degeneration, a follicular developmental fate that reduces female
fertility and is triggered by granulosa cell (GC) apoptosis, have been induced by dozens of …

miR-486 responds to apoptosis and autophagy by repressing SRSF3 expression in ovarian granulosa cells of dairy goats

S Liu, Q Bu, J Tong, Z Wang, J Cui, H Cao… - International Journal of …, 2023 - mdpi.com
The accumulation of ovarian granulosa cell (GC) apoptosis underlies follicular atresia. By
comparing the previous sequencing results, miR-486 was found to be differentially …