miR-218 promotes dopaminergic differentiation and controls neuron excitability and neurotransmitter release through the regulation of a synaptic-related genes …

S Pulcrano, R De Gregorio, C De Sanctis… - Journal of …, 2023 - Soc Neuroscience
In the brain, microRNAs (miRNAs) are believed to play a role in orchestrating synaptic
plasticity at a higher level by acting as an additional mechanism of translational regulation …

microRNAs in neurons: manifold regulatory roles at the synapse

G Siegel, R Saba, G Schratt - Current opinion in genetics & development, 2011 - Elsevier
The regulation of synapse formation and plasticity in the developing and adult brain
underlies a complex interplay of intrinsic genetic programs and extrinsic factors. Recent …

MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis

M Dori, D Cavalli, M Lesche, S Massalini… - …, 2020 - journals.biologists.com
MicroRNAs (miRNAs) are short (∼ 22 nt) single-stranded non-coding RNAs that regulate
gene expression at the post-transcriptional level. Over recent years, many studies have …

MicroRNA networks direct neuronal development and plasticity

NFM Olde Loohuis, A Kos, GJM Martens… - Cellular and Molecular …, 2012 - Springer
MicroRNAs (miRNAs) constitute a class of small, non-coding RNAs that act as post-
transcriptional regulators of gene expression. In neurons, the functions of individual miRNAs …

MicroRNAs as neuronal fate determinants

M Åkerblom, J Jakobsson - The Neuroscientist, 2014 - journals.sagepub.com
Since the discovery of short, regulatory microRNAs (miRNA) 20 years ago, the
understanding of their impact on gene regulation has dramatically increased. Differentiation …

Context-dependent functions of specific microRNAs in neuronal development

FB Gao - Neural development, 2010 - Springer
MicroRNAs (miRNAs) are small noncoding RNAs that regulate multiple developmental
processes at the post-transcriptional level. Recent rapid progresses have demonstrated …

The brain-enriched microRNA miR-9-3p regulates synaptic plasticity and memory

SE Sim, CS Lim, JI Kim, D Seo, H Chun… - Journal of …, 2016 - Soc Neuroscience
MicroRNAs (miRNAs) are small, noncoding RNAs that posttranscriptionally regulate gene
expression in many tissues. Although a number of brain-enriched miRNAs have been …

[HTML][HTML] Specification of neural cell fate and regulation of neural stem cell proliferation by microRNAs

JT Pham, GI Gallicano - American journal of stem cells, 2012 - ncbi.nlm.nih.gov
In the approximately 20 years since microRNAs (miRNAs) were first characterized, they
have been shown to play important roles in diverse physiologic functions, particularly those …

miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1

VY Poon, M Gu, F Ji, AM VanDongen, M Fivaz - BMC genomics, 2016 - Springer
Background MicroRNAs (miRNAs) are short non-coding RNAs that are emerging as
important post-transcriptional regulators of neuronal and synaptic development. The precise …

microRNAs at the synapse

G Schratt - Nature Reviews Neuroscience, 2009 - nature.com
MicroRNAs (miRNAs) are emerging as key modulators of post-transcriptional gene
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …